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World J Gastrointest Pathophysiol. Aug 15, 2014; 5(3): 359-365
Published online Aug 15, 2014. doi: 10.4291/wjgp.v5.i3.359
Published online Aug 15, 2014. doi: 10.4291/wjgp.v5.i3.359
Risk of cardiovascular disease in inflammatory bowel disease
Nynne Nyboe Andersen, Tine Jess, Department of Epidemiology Research, Statens Serum Institut, DK-2300 Copenhagen, Denmark
Author contributions: Andersen NN collected the material and drafted the manuscript; Jess T discussed the topic and revised the manuscript.
Correspondence to: Nynne Nyboe Andersen, MD, Department of Epidemiology Research, Statens Serum Institut, Artillerivej 5, DK-2300 Copenhagen S, Denmark. nyna@ssi.dk
Telephone: +45-32-683139 Fax: +45-32-683165
Received: December 11, 2013
Revised: April 22, 2014
Accepted: May 28, 2014
Published online: August 15, 2014
Processing time: 266 Days and 12.8 Hours
Revised: April 22, 2014
Accepted: May 28, 2014
Published online: August 15, 2014
Processing time: 266 Days and 12.8 Hours
Core Tip
Core tip: The increased risk of venous thromboembolic events in inflammatory bowel disease (IBD) patients is well-established and prophylactic strategies are implemented in current guidelines. The risk of arterial thromboembolic complications in IBD remains uncertain. Together, the systemic inflammation in patients with IBD and the inflammation-driven development of atherosclerosis form the basis of a potential association between the two disease entities. The present review will provide a summary of the existing literature on the association between IBD and thromboembolic diseases and discuss potential risk and preventive factors.