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World Journal of Radiology
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1949-8470
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study
©Author(s) (or their employer(s)) 2026.
World J Radiol. Feb 28, 2026; 18(2): 116462
Published online Feb 28, 2026. doi: 10.4329/wjr.v18.i2.116462
Table 1 Demographic features of patients with soft-tissue sarcomas receiving surgical resection, n (%)
Variable
All subjects (n = 638)
Training cohort (n = 447)
Testing cohort (n = 191)
P value
Age (year), median (IQR)49 (24)49 (24)47 (26)0.524
Age (year)0.259
< 65528 (82.8)365 (81.7)163 (85.3)
≥ 65110 (17.2)82 (18.3)28 (14.7)
Gender0.780
Male342 (53.6)238 (53.2)104 (54.5)
Female296 (46.4)209 (46.8)87 (45.5)
Location of primary tumor0.140
Trunk501 (78.5)344 (77.0)157 (82.2)
Limb137 (21.5)103 (23.0)34 (17.8)
Subtype0.454
Liposarcoma127 (19.9)88 (19.7)39 (20.4)
Rhabdomyosarcoma69 (10.8)56 (12.5)13 (6.8)
Synovial sarcoma69 (10.8)48 (10.7)21 (11.0)
Undifferentiated sarcoma108 (16.9)73 (16.3)35 (18.3)
Leiomyosarcoma111 (17.4)77 (17.2)34 (17.8)
Fibrosarcoma154 (24.1)105 (23.5)49 (25.7)
Stage0.437
I334 (52.4)234 (52.3)100 (52.4)
II216 (33.9)156 (34.9)60 (31.4)
III + IV88 (13.8)57 (12.8)31 (16.2)
Maximum diameter of tumor, (cm)0.435
< 10.0403 (63.2)278 (62.2)125 (65.4)
≥ 10.0235 (36.8)169 (37.8)66 (34.6)
BMI rank0.165
Underweight75 (11.8)57 (12.8)18 (9.4)
Normal426 (66.8)301 (67.3)125 (65.4)
Overweight129 (20.2)82 (18.3)47 (24.6)
Obese8 (1.3)7 (1.6)1 (0.5)
SII0.765
< 619.85423 (66.3)298 (66.7)125 (65.4)
≥ 619.85215 (33.7)149 (33.3)66 (34.6)
CRP0.838
< 5.0518 (81.2)362 (81.0)156 (81.7)
≥ 5.0120 (18.8)85 (19.0)35 (18.3)
CONUT score0.792
0-2551 (86.4)385 (86.1)166 (86.9)
3-1287 (13.6)62 (13.9)25 (13.1)
MUST group0.355
Low risk407 (63.8)279 (62.4)128 (67.0)
Medium risk102 (16.0)71 (15.9)31 (16.2)
High risk129 (20.2)97 (21.7)32 (16.8)
Subcutaneous adiposity0.240
No383 (60.0)275 (61.5)108 (56.5)
Yes255 (40.0)172 (38.5)83 (43.5)
Visceral adiposity0.093
No313 (49.1)229 (51.2)84 (44.0)
Yes325 (50.9)218 (48.8)107 (56.0)
Sarcopenia0.523
No315 (49.4)217 (48.5)98 (51.3)
Yes323 (50.6)230 (51.5)93 (48.7)
CT-derived index, median (IQR)
TAI89.67 (52.30)87.92 (54.07)92.30 (50.27)0.259
SAI46.47 (30.28)45.22 (31.66)51.20 (27.91)0.194
VAI36.34 (31.77)36.14 (31.18)37.85 (33.30)0.350
SMI45.35 (11.43)44.90 (11.63)46.35 (10.83)0.056
Complication0.422
No481 (75.4)341 (76.3)140 (73.3)
Yes157 (24.6)106 (23.7)51 (26.7)
Outcomes, median (IQR)
Length of hospitalization (day)12 (12)12 (12)10 (10)0.093
Progression-free survival (month)25 (37)26 (37)25 (34)0.943
Overall survival (month)35 (33)36 (32)32 (32)0.129
P value are obtained from χ2 tests for categorical variables and Mann-Whitney tests for continuous variables because of its non-normal distribution. Interquartile range describing the range between the first quartile and the third quartile for variables with non-normal distribution representing their discreteness. IQR: Interquartile range; BMI: Body mass index; SII: Systematic inflammatory index; CRP: C-reaction protein; CONUT: Controlling nutritional score; CT: Computed tomography; TAI: Total adipose tissue index; SAI: Subcutaneous adipose tissue index; VAI: Visceral adipose tissue index; SMI: Skeletal muscle index; MUST: Malnutrition universal screening tool.
Full Size Table
Table 2 Prediction accuracy of nomogram
VariableC-index
Brier score
Three-year
Five-year
Three-year
Five-year
PFSCox selectionRSF selectionCox selectionRSF selectionCox selectionRSF selectionCox selectionRSF selection
Training cohort0.635 (0.576-0.694)0.659 (0.600-0.718)0.653 (0.574-0.733)0.695 (0.614-0.776)23.4 (13.5-33.2)22.9 (13.3-32.5)22.9 (10.5-35.2)22.2 (10.2-34.2)
Testing cohort0.601 (0.504-0.698)0.675 (0.583-0.767)0.615 (0.482-0.749)0.702 (0.586-0.817)23.6 (17.0-30.1)22.3 (16.0-28.6)23.5 (14.7-32.3)21.6 (13.6-29.7)
OS
Training cohort0.573 (0.511-0.634)0.581 (0.519-0.642)0.660 (0.595-0.724)0.657 (0.592-0.723)22.4 (20.0-24.9)22.3 (19.8-24.8)18.8 (16.8-20.9)18.7 (16.7-20.8)
Testing cohort0.474 (0.378-0.569)0.473 (0.377-0.568)0.564 (0.444-0.684)0.584 (0.466-0.703)25.8 (22.3-29.3)25.6 (22.1-29.0)19.4 (16.0-22.9)19.2 (15.8-22.6)
Prediction accuracy of nomogram using different variable selection methods for progression-free survival and overall survival in the training and testing sets of patients with soft-tissue sarcomas receiving surgical resection. OS: Overall survival; PFS: Progression-free survival; RSF: Random survival forest.
Full Size Table
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