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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Radiol. May 28, 2026; 18(5): 118851
Published online May 28, 2026. doi: 10.4329/wjr.v18.i5.118851
Journey through technological advancements in radiation therapy
Pratibha Singh, Manoj Kumar Singh, Atul Mishra
Pratibha Singh, Manoj Kumar Singh, Department of Physics, Institute of Applied Sciences and Humanities, GLA University, Mathura 281406, Uttar Pradesh, India
Pratibha Singh, Department of Radiation Oncology, Mahatma Gandhi Medical College and Hospital, Jaipur 302022, Rajasthan, India
Atul Mishra, Department of Radiation Oncology, Uttar Pradesh University of Medical Sciences, Etawah 206130, Uttar Pradesh, India
Author contributions: Singh P conceptualized the review, performed the literature search, extracted and analyzed the data, and drafted the manuscript; Mishra A contributed to critical revisions and editorial improvements; Singh MK reviewed the manuscript and approved the final manuscript; all authors approved the final manuscript.
AI contribution statement: During the preparation of this manuscript, the author(s) used ChatGPT (OpenAI) to improve language clarity and readability. After using this tool, the author(s) reviewed and edited the content as needed and took full responsibility for the content of the publication.
Conflict-of-interest statement: The authors declare no conflict of interest.
Corresponding author: Atul Mishra, PhD, Associate Professor, Department of Radiation Oncology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah 206130, Uttar Pradesh, India. meetatulmishra@gmail.com
Received: January 13, 2026
Revised: February 12, 2026
Accepted: March 16, 2026
Published online: May 28, 2026
Processing time: 134 Days and 20.7 Hours
Core Tip

Core Tip: This review outlines the advancement of medical accelerators over time, showing how radiation therapy (RT) has evolved from early treatment machines to modern clinical systems. It focuses on the gradual improvement in treatment accuracy, reliability, and clinical usability. The review highlights how each generation of medical accelerators contributed to better patient care by enabling more precise dose delivery, improved treatment consistency, and safer clinical practice. By presenting this chronological progression in a clear and accessible manner, the article helps readers understand how long-term technological development in medical accelerators has shaped present-day RT and continues to influence ongoing research and future directions.

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