Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Radiol. Mar 28, 2026; 18(3): 117599
Published online Mar 28, 2026. doi: 10.4329/wjr.v18.i3.117599
Published online Mar 28, 2026. doi: 10.4329/wjr.v18.i3.117599
Predictive model for vedolizumab efficacy in moderate-to-severe ulcerative colitis based on computed tomography-derived body compositions and nutritional inflammatory markers
Xiao-Yan Zhang, Yu-Kun Li, Zi-Bin Tian, Ke-Yu Ren, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Qing-Yu Guo, Department of Gastroenterology, School of Nursing, Qingdao University, Qingdao 266000, Shandong Province, China
Jing-Nong Liu, Department of Gastroenterological Surgery, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Rui-Qing Liu, Department of Gastrointestinal Surgery, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Co-first authors: Xiao-Yan Zhang and Yu-Kun Li.
Co-corresponding authors: Rui-Qing Liu and Ke-Yu Ren.
Author contributions: Zhang XY and Li YK contributed equally to this article, they are the co-first authors of this manuscript; Zhang XY, Tian ZB, Liu RQ, and Ren KY designed the research study; Zhang XY, Li YK, Guo QY, and Liu JN performed the research; Liu RQ and Ren KY contributed equally to this article, they are the co-corresponding authors of this manuscript; and all authors thoroughly reviewed and endorsed the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the Affiliated Hospital of Qingdao University, approval No. QYFYWZLL30641.
Informed consent statement: Informed consent was waived by the Ethics Committee of the Affiliated Hospital of Qingdao University due to the retrospective design and the use of de-identified patient data that could not be linked to individuals.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The datasets analyzed during the current study are not publicly available due to patient privacy concerns but are available from the corresponding author on reasonable request.
Corresponding author: Ke-Yu Ren, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, No. 1677 Wutaishan Road, Qingdao 266000, Shandong Province, China.
Received: December 11, 2025
Revised: January 20, 2026
Accepted: March 5, 2026
Published online: March 28, 2026
Processing time: 105 Days and 13.9 Hours
Revised: January 20, 2026
Accepted: March 5, 2026
Published online: March 28, 2026
Processing time: 105 Days and 13.9 Hours
Core Tip
Core Tip: Combined assessment of intramuscular adipose tissue, C-reactive protein levels, skeletal muscle mass and he