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Retrospective Study
Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Jan 28, 2026; 18(1): 114552
Published online Jan 28, 2026. doi: 10.4329/wjr.v18.i1.114552
Clinical and radiographic feature of pulmonary nocardiosis: A study of 102 cases
Hui-Juan Wang, Yi-Ning Zhang, Li An
Hui-Juan Wang, Yi-Ning Zhang, Li An, Department of Respiratory and Critical Care Medicine, Beijing Chaoyang Hospital, Beijing Institute of Respiratory Medicine, Capital Medical University, Beijing 100020, China
Author contributions: Wang HJ wrote the manuscript; Wang HJ and An L designed the study; Zhang YN collected the patients’ clinical data; and all authors have read and approved the final version.
Supported by the Hospital-Level Incubation Project, No. CYFH202318; the National Major Science and Technology Project of the National Health Commission, No. 2024ZD0529603; and Beijing Tech Nova Program Cross-Cooperation Project.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Beijing Chaoyang Hospital, Beijing Institute of Respiratory Medicine, Capital Medical University, approval No. 2025-ke-359.
Informed consent statement: All patients gave their full informed consent for participation in this study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author bjzy818@sina.com.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li An, Professor, Department of Respiratory and Critical Care Medicine, Beijing Chaoyang Hospital, Beijing Institute of Respiratory Medicine, Capital Medical University, No. 8 Gongti South Road, Beijing 100020, China. bjzy818@sina.com
Received: September 28, 2025
Revised: October 24, 2025
Accepted: December 11, 2025
Published online: January 28, 2026
Processing time: 119 Days and 21.7 Hours
Core Tip

Core Tip: This study highlights that bronchiectasis is the most common comorbidity in pulmonary nocardiosis. Metagenomic next-generation sequencing is a key diagnostic tool. Crucially, chest computed tomography reveals distinct imaging patterns: Nocardia wallacei primarily presents as bronchopneumonia, while other species more frequently cause consolidation with nodules/cavities. Immunosuppressed patients exhibit more diverse and complex imaging features.