Scientometrics
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Apr 28, 2025; 17(4): 101636
Published online Apr 28, 2025. doi: 10.4329/wjr.v17.i4.101636
Structural and temporal dynamics analysis on immune response in low-dose radiation: History, research hotspots and emerging trends
Shu-Yuan Wang, Jia-Xing Wu, Xian An, Zhen Yuan, Yi-Fan Ren, Xiu-Feng Yu, Xiao-Dong Tian, Wei Wei
Shu-Yuan Wang, Jia-Xing Wu, Zhen Yuan, Yi-Fan Ren, School of Medicine, Nankai University, Tianjin 300071, China
Xian An, Wei Wei, Department of Radiotherapy, Chinese PLA General Hospital, Beijing 100071, China
Xiu-Feng Yu, Department of General Medicine, Tuberculosis Hospital of Shaanxi Province, Xi’an 710105, Shaanxi Province, China
Xiao-Dong Tian, Department of Thoracic Surgery, Chinese PLA General Hospital, Beijing 100853, China
Co-first authors: Shu-Yuan Wang and Jia-Xing Wu.
Co-corresponding authors: Xiao-Dong Tian and Wei Wei.
Author contributions: Wang SY and Wu JX contributed equally to this work, developed the methodology, collected data, analyzed and interpreted data, written manuscript; An X, Yuan Z, Ren YF and Yu XF contributed materials and experimented; Both Tian XD and Wei W have played important and indispensable roles in the revision and review of manuscript, manuscript preparation and supervision of the research as the co-corresponding authors. Wei W searched the literature, revised and submitted the early version of the manuscript. He took primary responsibility for communication with the journal during the manuscript submission, peer review, and publication processes. He also ensured that all the journal’s administrative requirements were properly completed. Tian XD was responsible for data re-analysis and re-interpretation, comprehensive literature search, preparation and submission of the current version of the manuscript with an in-depth interpretation of the discussion on the temporal dynamics of the immune response. He was also instrumental in improving the overall readability and scientific rigor of the paper. This collaboration between Tian XD and Wei W is crucial for the publication of this manuscript. All authors contributed to the article and approved the submitted version.
Supported by National Natural Science Foundation of China, No. 82103783; and Guangdong Provincial Foundation for Basic and Applied Basic Research - Regional Joint Fund, No. 2020A1515110809.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei Wei, MD, PhD, Postdoctoral Fellow, Department of Radiotherapy, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100071, China. dr_weiwei528@163.com
Received: September 21, 2024
Revised: December 19, 2024
Accepted: March 27, 2025
Published online: April 28, 2025
Processing time: 212 Days and 14.7 Hours
Core Tip

Core Tip: This study provides a comprehensive bibliometric analysis of the immune response to low-dose radiotherapy (LDR) over the past two decades. It highlights key research trends, influential studies, and emerging hotspots such as ipilimumab and targeted therapy. Through structural and temporal dynamics, the analysis offers insights into global collaborations and the evolution of research themes, guiding future investigations in LDR. The findings are valuable for clinicians and researchers, helping to optimize therapeutic strategies and advance the field of radiotherapy.