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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Radiol. Jan 28, 2025; 17(1): 99207
Published online Jan 28, 2025. doi: 10.4329/wjr.v17.i1.99207
Published online Jan 28, 2025. doi: 10.4329/wjr.v17.i1.99207
Whole-body magnetic resonance imaging provides accurate staging of diffuse large B-cell lymphoma, but is less preferred by patients
Lukas Lambert, Department of Imaging Methods, Motol University Hospital and Second Faculty of Medicine, Charles University, Prague 15006, Czech Republic
Monika Wagnerova, Andrea Burgetova, Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague 12808, Czech Republic
Prokop Vodicka, Katerina Benesova, Marek Trneny, First Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague 12808, Czech Republic
David Zogala, Institute of Nuclear Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague 12808, Czech Republic
Author contributions: Lambert L, Trneny M, Zogala D and Burgetova A contributed to conceptualization; Lambert L and Trneny M contributed to methodology; Lambert L, Wagnerova M, Vodicka P, Benesova K, Zogala D, Trneny M and Burgetova A contributed to data collection, writing review and editing; Lambert L and Vodicka P contributed to data analysis, writing original draft; Lambert L contributed to visualization.
Supported by the Czech Ministry of Health, General University Hospital in Prague, No. VFN00064165.
Institutional review board statement: This single-center prospective study was performed in accordance with the Declaration of Helsinki (rev. 2013) and approved by the Ethics Committee of the General University Hospital in Prague.
Clinical trial registration statement: Observational study (not registered) as a sub-study of the Czech Lymphoma Study Group (No. NCT03199066).
Informed consent statement: All participants signed an informed consent.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement: All data are available upon reasonable request to the corresponding author.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lukas Lambert, PhD, Professor, Department of Imaging Methods, Motol University Hospital and Second Faculty of Medicine, Charles University, V Úvalu 84, 15006 Praha 5, Prague 15006, Czech Republic. lukas.lambert@vfn.cz
Received: July 16, 2024
Revised: December 8, 2024
Accepted: December 25, 2024
Published online: January 28, 2025
Processing time: 188 Days and 13.4 Hours
Revised: December 8, 2024
Accepted: December 25, 2024
Published online: January 28, 2025
Processing time: 188 Days and 13.4 Hours
Core Tip
Core Tip: Although the agreement in nodal and extranodal involvement by diffuse large-cell B lymphoma is excellent, patients are less willing to undergo whole-body magnetic resonance imaging (wbMRI) as a second examination parallel to positron emission tomography/computed tomography. wbMRI is less well accepted, and patients are concerned about the enclosed environment and duration of the MRI examination. The measurements of lymph node dimensions and quantification of restricted diffusion are not better guides of nodal involvement than visual assessment by an experienced radiologist. Diffusion weighted images with background suppression and contrast-enhanced T1 were the most useful sequences in wbMRI, allowing the imaging protocol to be shortened.