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World J Radiol. Mar 28, 2013; 5(3): 126-142
Published online Mar 28, 2013. doi: 10.4329/wjr.v5.i3.126
Evaluation of cancer treatment in the abdomen: Trends and advances
Silanath Peungjesada, Hubert H Chuang, Srinivasa R Prasad, Haesun Choi, Evelyne M Loyer, Yulia Bronstein
Silanath Peungjesada, Srinivasa R Prasad, Haesun Choi, Evelyne M Loyer, Department of Diagnostic Radiology, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, United States
Hubert H Chuang, Department of Nuclear Medicine, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, United States
Yulia Bronstein, Virtual Radiologic, 11995 Singletree Ln, Suite 500, Eden Prairie, MN 55344, United States
Author contributions: All authors contributed equally to the pepar.
Correspondence to: Evelyne M Loyer, MD, Department of Diagnostic Radiology, University of Texas, MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, United States. eloyer@mdanderson.org
Telephone: +1-713-7922022 Fax: +1-713-7922022
Received: June 4, 2012
Revised: January 24, 2013
Accepted: January 31, 2013
Published online: March 28, 2013
Abstract

Response evaluation in Oncology has relied primarily on change in tumor size. Inconsistent results in the prediction of clinical outcome when size based criteria are used and the increasing role of targeted and loco-regional therapies have led to the development of new methods of response evaluation that are unrelated to change in tumor size. The goals of this review are to expose briefly the size based criteria and to present the non-size based approaches that are currently applicable in the clinical setting. Other paths that are still being explored are not discussed in details.

Keywords: Evaluation; Cancer treatment; Abdomen