Published online Apr 28, 2025. doi: 10.4329/wjr.v17.i4.106186
Revised: March 19, 2025
Accepted: April 11, 2025
Published online: April 28, 2025
Processing time: 63 Days and 3.2 Hours
This study highlights the significance of considering pituitary neuroendocrine tumor volume when determining the appropriate line of therapy for patients with acromegaly. The findings suggest that, although tumor volume may assist in predicting the need for more aggressive treatment strategies, it is not a reliable indicator of disease persistence following surgical intervention. Further research is warranted to investigate additional factors influencing acromegaly treatment outcomes to enhance patient care.
Core Tip: Pituitary neuroendocrine tumor volume serves as a complementary prognostic factor for disease control in patients with acromegaly. Larger tumors are associated with a higher risk of persistent disease and an increased likelihood of requiring medical treatment following surgery. The consideration of tumor volume is essential in clinical decision-making when managing acromegaly.
