Optical coherence tomography-guided percutaneous coronary intervention compared to angiography-guided percutaneous coronary intervention for complex lesions

doi:10.4330/wjc.v17.i9.110403

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Sep 26, 2025 (publication date) through Sep 17, 2025

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Cardiol. Sep 26, 2025; 17(9): 110403
Published online Sep 26, 2025. doi: 10.4330/wjc.v17.i9.110403

Table 1 Baseline characteristics of included studies, n (%)

Ref.	Study design	Follow-up duration	Stent type	Sample size		Age (years), mean (SD)		Gender (male)		Left ventricular ejection fraction (%), mean (SD)		Current smoking		Diabetes mellitus		Hypertension		Prior myocardial infarction
Ref.	Study design	Follow-up duration	Stent type	OCT-PCI	Angio-PCI	OCT-PCI	Angio-PCI	OCT-PCI	Angio-PCI	OCT-PCI	Angio-PCI	OCT-PCI	Angio-PCI	OCT-PCI	Angio-PCI	OCT-PCI	Angio-PCI	OCT-PCI	Angio-PCI
CALIPSO, 2025, Amabile et al[15]	RCT	1 month	DES (everolimus)	65	69	71.17 (8.72)	73.83 (7.95)	52 (80)	57 (83)	58.33 (11.37)	58 (10.60)	8 (12)	10 (15)	24 (37)	27 (39)	46 (71)	43 (62)	-	-
LUMIEN IV Sub-study, 2024, Ali et al[11]	RCT, Sub-analysis	24 months	DES (everolimus)	992	981	65.6 (10.5)	65.7 (10.4)	792 (79.8)	750 (76.5)	55.1 (8.5)	55.1 (8.5)	198 (20)	192 (19.6)	360 (36.3)	342 (34.9)	707 (71.3)	734 (74.8)	211 (21.3)	255 (26.0)
OCCUPI, 2024, Hong et al[14]	RCT	12 months	DES (everolimus)	803	801	63.67 (9.65)	64.0 (8.91)	646 (80)	644 (80)	59.5 (8.8)	59.5 (8.8)	149 (19)	158 (20)	261 (33)	262 (33)	466 (58)	451 (56)	40 (5)	42 (5)
OCTOBER, 2023, Holm et al[12]	RCT	24 months	DES (everolimus)	600	601	66.4 (10.5)	66.2 (9.9)	473 (78.8)	475 (79.0)	56.50 (7.43)	56.50 (7.43)	77 (12.8)	85 (14.1)	103 (17.2)	97 (16.1)	422 (70.3)	448 (74.5)	170 (28.3)	180 (30.0)
RENOVATE-COMPLEX-PCI, 2024, Lee et al[13]	RCT, Sub-analysis	25.2 months	DES (everolimus)	278	547	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Detailed baseline characteristics for the RENOVATE-COMPLEX PCI, 2024 were not detailed for the optical coherence tomography-guided percutaneous coronary intervention (PCI) subgroup within the intravascular ultrasound guided PCI. Angio-PCI: Angiography-guided percutaneous coronary intervention; DES: Drug-eluting stent; OCT-PCI: Optical coherence tomography-guided percutaneous coronary intervention; RCT: Randomized controlled trial.

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Citation: Burhan M, Saeed H, Usama M, Tariq A, Shafiq S, Hurjkaliani S, Iqbal M, Shahid S, Khalid S, Tahirkheli NK. Optical coherence tomography-guided percutaneous coronary intervention compared to angiography-guided percutaneous coronary intervention for complex lesions. World J Cardiol 2025; 17(9): 110403
URL: https://www.wjgnet.com/1949-8462/full/v17/i9/110403.htm
DOI: https://dx.doi.org/10.4330/wjc.v17.i9.110403