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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Jan 26, 2026; 18(1): 113579
Published online Jan 26, 2026. doi: 10.4330/wjc.v18.i1.113579
Published online Jan 26, 2026. doi: 10.4330/wjc.v18.i1.113579
Genetic insights into coronary heart disease in the Teochew population: Bridging gaps in precision medicine
Zu-Chian Chiang, Biomedical Research Center of South China, Fujian Key Laboratory of Innate Immune Biology, College of Life Science, Fujian Normal University, Fuzhou 350117, Fujian Province, China
Xi Huang, Department of Cardiology, The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou 350000, Fujian Province, China
Author contributions: Chiang ZC conceived the study, drafted, reviewed, and edited the initial manuscript, revised the manuscript, and provided resources and proofreading; Huang X drafted the initial manuscript, revised the manuscript, and provided resources.
Supported by Fujian Province Science and Technology Innovation Joint Fund Project Plan, No. 2024Y9530.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xi Huang, Chief Physician, Department of Cardiology, The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, No. 363 Guobing Avenue, Fuzhou 350000, Fujian Province, China. huangxi@fjtcm.edu.cn
Received: August 29, 2025
Revised: October 1, 2025
Accepted: December 25, 2025
Published online: January 26, 2026
Processing time: 139 Days and 15.4 Hours
Revised: October 1, 2025
Accepted: December 25, 2025
Published online: January 26, 2026
Processing time: 139 Days and 15.4 Hours
Core Tip
Core Tip: This editorial emphasizes that APOE ε2 and higher LPA KIV-2 copy number are associated with a reduced risk of coronary heart disease in the Teochew population, highlighting the value of population-specific genetic studies for tailored cardiovascular care.