Copyright
©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Jan 26, 2026; 18(1): 113258
Published online Jan 26, 2026. doi: 10.4330/wjc.v18.i1.113258
Published online Jan 26, 2026. doi: 10.4330/wjc.v18.i1.113258
Frailty in acute coronary syndrome: From risk stratification to clinical decision-making
Ioanna Dimitriadou, Evangelos C Fradelos, Aikaterini Toska, Maria Saridi, Department of Nursing, Laboratory of Clinical Nursing, University of Thessaly, Larisa 41500, Thessalía, Greece
John Skoularigis, Department of Cardiology, University Hospital of Larisa, Larisa 41110, Thessalía, Greece
Author contributions: Dimitriadou I and Toska A drafted the manuscript; Dimitriadou I and Saridi M were responsible for study design and conceptualization; Fradelos EC and Skoularigis J performed the investigation; Saridi M provided supervision of the overall project. All authors have read and approve the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ioanna Dimitriadou, Academic Fellow, Department of Nursing, Laboratory of Clinical Nursing, University of Thessaly, Trikala Ring Road, Larisa 41500, Thessalía, Greece. iwannadimitriadou07@gmail.com
Received: August 21, 2025
Revised: September 15, 2025
Accepted: November 18, 2025
Published online: January 26, 2026
Processing time: 147 Days and 12.1 Hours
Revised: September 15, 2025
Accepted: November 18, 2025
Published online: January 26, 2026
Processing time: 147 Days and 12.1 Hours
Core Tip
Core Tip: Frailty is increasingly recognized as a crucial determinant of outcomes in patients with acute coronary syndrome. This mini review highlights the most widely used frailty assessment tools, their prognostic value, and their practical application in emergency and inpatient cardiology settings. By summarizing current evidence and proposing a pragmatic pathway for integrating frailty into decision-making, the review underscores how simple bedside screening can guide individualized care, improve risk prediction, and support cardio-geriatric collaboration in managing older adults with acute coronary syndrome.