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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Sep 26, 2025; 17(9): 109876
Published online Sep 26, 2025. doi: 10.4330/wjc.v17.i9.109876
Published online Sep 26, 2025. doi: 10.4330/wjc.v17.i9.109876
From joints to vessels: How rheumatoid arthritis therapy alters the fate of the heart
Liudmila A Zotova, Nikita V Enenkov, Department of Hospital Therapy with a Course of Medical and Social Expertise, The Federal State Budgetary Educational Institution of Higher Education “Ryazan State Medical University named after Academician I.P. Pavlov” of the Ministry of Health of the Russian Federation, Ryazan 390026, Ryazanskaya Oblast’, Russia
Author contributions: Zotova LA: Conceptualization, investigation, writing-original draft, writing- review & editing, visualization, validation, formal analysis; Enenkov NV: Formal analysis, writing-original draft. All authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Liudmila A Zotova, PhD, Assistant Professor, Department of Hospital Therapy with a Course of Medical and Social Expertise, The Federal State Budgetary Educational Institution of Higher Education “Ryazan State Medical University named after Academician I.P. Pavlov” of the Ministry of Health of the Russian Federation, Stroikova, 96, Ryazan 390026, Ryazanskaya Oblast’, Russia. dr.zotova@gmail.com
Received: May 26, 2025
Revised: June 12, 2025
Accepted: August 28, 2025
Published online: September 26, 2025
Processing time: 116 Days and 9.2 Hours
Revised: June 12, 2025
Accepted: August 28, 2025
Published online: September 26, 2025
Processing time: 116 Days and 9.2 Hours
Core Tip
Core Tip: In this review, we analyze both the positive and negative influences on the cardiovascular system of all drugs currently used in rheumatological practice, including the most up-to-date therapies. Particular attention is given to the safety analysis of long-established drugs, whose effectiveness in treating rheumatoid arthritis is well established, while their cardiovascular safety has been studied to a much lesser extent.