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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Dec 26, 2025; 17(12): 110450
Published online Dec 26, 2025. doi: 10.4330/wjc.v17.i12.110450
Published online Dec 26, 2025. doi: 10.4330/wjc.v17.i12.110450
Temporal trends in characteristics and outcomes of patients undergoing percutaneous mitral valve repair
Rasha Kaddoura, Department of Pharmacy, Heart Hospital, Hamad Medical Corporation, Doha 3050, DA, Qatar
Zainab Dakhil, Department of Intervention, Ibn Al-Bitar Cardiac Center, Baghdad 00000, Iraq
Daoud Al-Badriyeh, College of Pharmacy, QU Health, Qatar University, Doha 2713, Qatar
Dina Abushanab, Drug Information Center, Hamad Medical Corporation, Doha 00000, Qatar
Ihsan Rafie, Mohammed Al-Hijji, Department of Cardiology, Heart Hospital, Hamad Medical Corporation, Doha 3050, Qatar
Author contributions: All authors have contributed equally to, read, and approved the manuscript
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rasha Kaddoura, PharmD, Department of Pharmacy, Heart Hospital, Hamad Medical Corporation, Al-Rumailah, Doha 3050, DA, Qatar.
Received: June 10, 2025
Revised: July 25, 2025
Accepted: November 7, 2025
Published online: December 26, 2025
Processing time: 201 Days and 4.3 Hours
Revised: July 25, 2025
Accepted: November 7, 2025
Published online: December 26, 2025
Processing time: 201 Days and 4.3 Hours
Core Tip
Core Tip: Patients with secondary mitral valve regurgitation from the real world who underwent transcatheter edge-to-edge repair of the mitral valve may show different characteristics and outcomes from those recruited in the landmark trials. Patients from the landmark trials may have overall favorable characteristics, but this did not translate into better outcomes over time. There were no major variations over time in terms of characteristics and outcomes when comparing patients from real-world and those from the landmark trials.