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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Oct 26, 2025; 17(10): 110962
Published online Oct 26, 2025. doi: 10.4330/wjc.v17.i10.110962
Published online Oct 26, 2025. doi: 10.4330/wjc.v17.i10.110962
Thoracic endovascular vs open surgical repair in descending thoracic aortic aneurysms: A systematic review and meta-analysis
Muneeb Khawar, Umad Ali, Syed Abdullah Shah, Muneeb Saifullah, Talha Iqbal, Shameer Iqbal Ghuman, Department of Medicine, King Edward Medical University, Lahore 54000, Punjab, Pakistan
Malik Abdullah Rasheed, Mirza Muhammad Hadeed Khawar, Department of Medicine, Services Institute of Medical Sciences, Lahore 54000, Punjab, Pakistan
Abdul Basit Rasheed, Department of Surgery, Pakistan Kidney and Liver Institute and Research Centre, Lahore 54000, Punjab, Pakistan
Sarmad Zain, Moosa Mubarika, Department of Medicine, Nishtar Medical University, Multan 66000, Punjab, Pakistan
Ikra Rana, Department of Medicine, International School of Medicine International University of Kyrgyzstan, Bishkek 720074, Kyrgyzstan
Prutha Pathak, Internal Medicine, North Alabama Medical Center, Florence, AL 35630, United States
Author contributions: Khawar M and Ali U conceptualized; Khawar M, Ali U, Shah SA, Zain S, Hadeed Khawar MM, Iqbal T, Ghuman SI, and Rana I performed data collation; Khawar M and Zain S were responsible for the methodology; Ali U, Rasheed MA, Rasheed AB, Saifullah M, and Mubarika M conducted a formal analysis; Khawar M, Ali U, Rasheed MA, and Rasheed AB wrote the original manuscript; Khawar M, Ali U, Rasheed MA, Rasheed AB, Shah SA, Zain S, Saifullah M, Mubarika M, Hadeed Khawar MM, Iqbal T, Ghuman SI, and Rana I wrote, reviewed, and edited; Prutha P conducted the final review; and all authors thoroughly reviewed and endorsed the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ikra Rana, MD, Department of Medicine, International School of Medicine International University of Kyrgyzstan, 6 Street, Bishkek 720074, Kyrgyzstan.
Received: June 19, 2025
Revised: July 11, 2025
Accepted: September 12, 2025
Published online: October 26, 2025
Processing time: 127 Days and 15.2 Hours
Revised: July 11, 2025
Accepted: September 12, 2025
Published online: October 26, 2025
Processing time: 127 Days and 15.2 Hours
Core Tip
Core Tip: Thoracic endovascular aortic repair may be the preferred strategy for many patients, particularly those with significant comorbidities or high surgical risk; treatment decisions should be carefully individualized. A comprehensive assessment of patient-specific factors, including anatomical suitability, overall health status, and institutional expertise, remains critical in determining whether an endovascular or open surgical approach is most appropriate. As technological advances and surgical techniques continue to refine, further studies will be essential in guiding optimal patient selection and improving long-term outcomes for descending thoracic aortic aneurysm repair.