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World J Cardiol. Jan 26, 2025; 17(1): 99595
Published online Jan 26, 2025. doi: 10.4330/wjc.v17.i1.99595
Pathogenic genes and clinical prognosis in hypertrophic cardiomyopathy
Ying Hong, Hu-Tao Xi, Xin-Yi Yang, Wilber W Su, Xiao-Ping Li
Ying Hong, Hu-Tao Xi, Xin-Yi Yang, Xiao-Ping Li, Institute of Cardiovascular Diseases & Department of Cardiology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610072, Sichuan Province, China
Ying Hong, Department of Cardiology, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan Province, China
Wilber W Su, Department of Cardiology, Banner-University Medical Center, Phoenix, AZ 85006, United States
Co-first authors: Ying Hong and Hu-Tao Xi.
Author contributions: Hong Y and Xi HT wrote the paper, they contributed equally as co-first authors; Yang XY searched for literature; Su WW and Li XP critically revised the manuscript; and all authors read, edited and approved the final manuscript.
Supported by National Natural Science Foundation of China, No. 81770379 and 81470521.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Ping Li, PhD, Associate Professor, Institute of Cardiovascular Diseases & Department of Cardiology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, No. 32 Section 2 West First Ring Road, Chengdu 610072, Sichuan Province, China. lixiaoping0119@163.com
Received: July 25, 2024
Revised: October 23, 2024
Accepted: December 27, 2024
Published online: January 26, 2025
Processing time: 179 Days and 17.9 Hours
Core Tip

Core Tip: Hypertrophic cardiomyopathy (HCM) is an autosomal dominant inherited cardiomyopathy with a highly variable clinical phenotype. This paper provides a detailed reference on the pathogenic genes of HCM and their phenotypic prognosis. These findings hold significant potential for guiding clinical decision-making, particularly in personalizing management strategies for HCM patients.