©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Nov 26, 2024; 16(11): 632-643
Published online Nov 26, 2024. doi: 10.4330/wjc.v16.i11.632
Published online Nov 26, 2024. doi: 10.4330/wjc.v16.i11.632
Cardiovascular and nonalcoholic fatty liver disease: Sharing common ground through SIRT1 pathways
Kenneth Maiese, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20810, United States
Author contributions: Maiese K conceived, designed, and wrote this article.
Supported by American Diabetes Association; American Heart Association; NIH NIEHS; NIH NIA; NIH NINDS; NS053956; and NIH ARRA.
Conflict-of-interest statement: The author reports no conflicts of interest for this article.
Corresponding author: Kenneth Maiese, MD, National Heart, Lung, and Blood Institute, National Institutes of Health, Cellular and Molecular Signaling, Bethesda, MD 20810, United States. wntin75@yahoo.com
Received: July 13, 2024
Revised: August 27, 2024
Accepted: October 10, 2024
Published online: November 26, 2024
Processing time: 109 Days and 17.2 Hours
Revised: August 27, 2024
Accepted: October 10, 2024
Published online: November 26, 2024
Processing time: 109 Days and 17.2 Hours
Core Tip
Core Tip: Cardiovascular disease is the principal cause of non-communicable diseases with individuals succumbing to heart disease every thirty-three seconds and has a significant comorbidity with nonalcoholic fatty liver disease (NAFLD). These two disorders impact millions of individuals across the globe, yield significant disability and death to individuals, and have a common underlying cellular pathway with silent mating type information regulation 2 homolog 1 (Saccharomyces cerevi