Published online Sep 26, 2022. doi: 10.4330/wjc.v14.i9.483
Peer-review started: April 9, 2022
First decision: May 31, 2022
Revised: May 31, 2022
Accepted: August 17, 2022
Article in press: August 17, 2022
Published online: September 26, 2022
Processing time: 163 Days and 10.9 Hours
Electrocardiogram (ECG) is a well-established, easily obtained, low-cost diagnostic tool that is the cornerstone of cardiological evaluation. ECG markers have been associated with the presence of myocardial fibrosis, as depicted from cardiac magnetic resonance (CMR) evaluation.
ECG can be a valuable tool for the risk stratification of sudden cardiac death in different clinical settings.
To elucidate the association of ECG markers with CMR-late gadolinium enhancement in different clinical settings.
Methodology of Systematic reviews in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA Statement).
Our results summarize the existing evidence about the association of ECG markers with fibrosis as identified by CMR. Existing data show that fragmented QRS, Q waves and repolarization abnormalities are some of the ECG indices that are associated with myocardial fibrosis.
Myocardial fibrosis, a marker of prognosis in a wide spectrum of clinical settings, can be easily identified by ECG indices.
Future research should be focused on the identification of ECG markers that are reliably associated with myocardial fibrosis in different clinical settings. Furthermore, the association of ECG markers with all-cause mortality and arrhythmic events is of great importance.