Published online Apr 26, 2026. doi: 10.4330/wjc.v18.i4.115113
Revised: November 18, 2025
Accepted: February 9, 2026
Published online: April 26, 2026
Processing time: 188 Days and 5.3 Hours
There is limited data availability regarding safety and feasibility of outpatient percutaneous coronary interventions (PCI).
To evaluate the short- and long-term outcomes of patients undergoing outpatient PCI with special regard to patients with left main and proximal left anterior descending artery disease.
The retrospective, single-center study was conducted in a hemodynamics laboratory dedicated to one-day procedures. We have analyzed short-, medium- and long-term outcomes of the patients undergoing PCI mostly from radial or ulnar access being discharged few hours after procedure.
During the follow-up period, 787 procedures were performed on 444 patients, including 25 procedures in the left main and 115 procedures in the proximal left anterior descending artery. The median time to discharge was 150 minutes. The median time of follow-up in the general group was 587 days. There was no myocardial infarction (MI), death, stroke or emergent bypass within 24 hours after surgery. During the 30 days of major adverse cardiac and cerebrovascular events follow-up, there were 1 MI (0.17%), 7 cases (0.88%) of target vessel revascularization (TVR) and 4 unplanned hospitalizations (0.7%); there were no deaths or strokes. During 720 days of major adverse cardiac and cerebrovascular events follow-up, there were 11 deaths (1.93%), 5 MIs (0.88%), 60 cases of TVR (7.62%), and 1 stroke (0.17%). Cases of repeat revascularization were observed more often in combined group of patients with diabetes or pre-diabetes than in patients without these conditions (P = 0.046). Patients who underwent PCI with femoral access were statistically more likely to undergo repeat revascularization within 2 years after the procedure [19 (21.84%) vs 41 (5.85%) P < 0.001]. There was a statistically significant higher prevalence of TVR within 2 years after the procedure in patients who had more than one lesion treated compared to single lesion procedures [22 (11.70%) vs 38 (6.34%); P = 0.015].
The results of this study suggest that PCIs performed on an outpatient basis with very short discharge times may be safe and feasible. However, as this is a hypothesis- generating study, the present findings should be interpreted with caution and confirmed in future large- scale randomized controlled trials.
Core Tip: A single-center, retrospective study was conducted to evaluate the short- and long-term outcomes of patients undergoing outpatient percutaneous coronary interventions. During the follow-up period, 787 procedures were performed on 444 patients, including 25 procedures in the left main and 115 procedures in the proximal left anterior descending artery. Over the 720 days of major adverse cardiac and cerebrovascular events follow-up, there were 11 deaths (1.93%), 5 myocardial infarctions (0.88%), 60 cases of target vessel revascularization (7.62%), and 1 stroke (0.17%). The results of study suggest that percutaneous coronary interventions performed on an outpatient basis with very short discharge times may be safe and feasible.