Innate immunity and wound repair: The platelet-rich fibrin advantage

doi:10.4331/wjbc.v16.i2.107195

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Jun 5, 2025 (publication date) through Jun 26, 2025

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World Journal of Biological Chemistry

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1949-8454

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Biol Chem. Jun 5, 2025; 16(2): 107195
Published online Jun 5, 2025. doi: 10.4331/wjbc.v16.i2.107195

Innate immunity and wound repair: The platelet-rich fibrin advantage

Saeed Mohammadi

Saeed Mohammadi, Natural and Medical Sciences Research Center, University of Nizwa, Nizwa 616, Ad Dakhiliyah, Oman

Author contributions: Mohammadi S contributed to this paper, the writing and editing of the manuscript and review of literature, designed the overall concept and outline of the manuscript, read and approved the final version of the manuscript to be published.

Supported by The Oman Ministry of Higher Education, Research, and Innovation, No. BFP/RGP/HSS/24/015.

Conflict-of-interest statement: The author declares that there are no conflicts of interest to disclose.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Saeed Mohammadi, PhD, Assistant Professor, Natural and Medical Sciences Research Center, University of Nizwa, Birkat Al Mouz University of Nizwa Campus, Nizwa 616, Ad Dakhiliyah, Oman. s.mohammadi@unizwa.edu.om

Received: March 18, 2025
Revised: April 11, 2025
Accepted: April 27, 2025
Published online: June 5, 2025
Processing time: 73 Days and 15.6 Hours

Core Tip

Core Tip: Platelet-rich fibrin (PRF) is a promising autologous blood product for enhanced wound healing. PRF modulates the inflammatory response and promotes tissue regeneration. Recent research highlights PRF's ability to accelerate wound closure, enhance tissue repair, and modulate the inflammatory response in an animal model.