Impact of diabetes mellitus history on postoperative infectious complications in gastric or colorectal cancer patients

doi:10.4240/wjgs.117631

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Jun 27, 2026; 18(6): 117631
Published online Jun 27, 2026. doi: 10.4240/wjgs.117631

Table 1 Univariate analysis of postoperative infectious complications in gastric/colorectal cancer patients, n (%)

Factor	Postoperative infection group (n = 48)	Non-infection group (n = 152)	χ² value	t value	P value
Age ≥ 65 years	32 (66.7)	56 (36.8)	13.607	-	< 0.001
Sex (male)	28 (58.3)	90 (59.2)	0.011	-	0.916
BMI (kg/m²), mean ± SD	23.54 ± 3.18	22.86 ± 3.43	-	1.318	0.189
History of diabetes	25 (52.1)	37 (24.3)	13.577	-	< 0.001
HbA1c ≥ 7.0%	22 (45.8)	30 (19.7)	13.261	-	< 0.001
Alb < 35 g/L	20 (41.7)	32 (21.1)	8.355	-	0.004
ASA score ≥ III	19 (39.6)	35 (23.0)	5.239	-	0.022
Tumor location (colorectal)	30 (62.5)	82 (53.9)	1.081	-	0.299
TNM stage (III-IV)	35 (72.9)	80 (52.6)	6.225	-	0.013
Surgical approach (open)	20 (41.7)	50 (32.9)	1.212	-	0.271
Operation time ≥ 180 minutes	36 (75.0)	78 (51.3)	8.379	-	0.004
Intraoperative blood loss ≥ 200 mL	18 (37.5)	45 (29.6)	1.052	-	0.305

BMI: Body mass index; HbA1c: Hemoglobin A1c; Alb: Albumin; ASA: American Society of Anesthesiologists; TNM: Tumor-node-metastasis.

Full Size Table

Table 2 Multivariate logistic regression analysis of postoperative infectious complications in gastric/colorectal cancer patients

Factor	β	Wald χ²	OR	95%CI	P value
History of diabetes	1.204	8.765	3.335	1.532-7.258	0.003
HbA1c ≥ 7.0%	1.876	12.341	6.524	2.456-17.329	< 0.001
Alb < 35 g/L	0.985	6.218	2.678	1.234-5.814	0.013
Age ≥ 65 years	0.672	3.112	1.958	0.912-4.205	0.078
ASA score ≥ III	0.501	1.876	1.651	0.754-3.614	0.171
TNM stage (III-IV)	0.587	2.654	1.799	0.823-3.931	0.103
Operation time ≥ 180 minutes	0.634	3.445	1.885	0.897-3.964	0.064

OR: Odds ratio; CI: Confidence interval; HbA1c: Hemoglobin A1c; Alb: Albumin; ASA: American Society of Anesthesiologists; TNM: Tumor-node-metastasis.

Full Size Table

Citation: Peng YY, Amannisha M, Chen LD. Impact of diabetes mellitus history on postoperative infectious complications in gastric or colorectal cancer patients. World J Gastrointest Surg 2026; 18(6): 117631
URL: https://www.wjgnet.com/1948-9366/full/v18/i6/117631.htm
DOI: https://dx.doi.org/10.4240/wjgs.117631

Peng YY, Amannisha M, Chen LD. Impact of diabetes mellitus history on postoperative infectious complications in gastric or colorectal cancer patients. World J Gastrointest Surg 2026; 18(6): 117631 [DOI: 10.4240/wjgs.117631]

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