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World J Gastrointest Surg. Jun 27, 2026; 18(6): 117631
Published online Jun 27, 2026. doi: 10.4240/wjgs.117631
Published online Jun 27, 2026. doi: 10.4240/wjgs.117631
Impact of diabetes mellitus history on postoperative infectious complications in gastric or colorectal cancer patients
Ying-Ying Peng, Department of Oncology, Zhebei Mingzhou Hospital, Huzhou 313000, Zhejiang Province, China
Maimaiti Amannisha, Department of Medical Oncology, Shache County People’s Hospital, Shache 844700, Xinjiang Uygur Autonomous Region, China
Li-Dan Chen, Department of Emergency, Xuchang Central Hospital, Xuchang 461000, Henan Province, China
Author contributions: Peng YY was responsible for the study design, data acquisition, and drafting of the manuscript; Amannisha M contributed to data analysis, interpretation, and manuscript preparation; Chen LD supervised the entire research process, provided critical revisions for intellectual content, and approved the final version for submission; and all authors thoroughly reviewed and endorsed the final manuscript.
AI contribution statement: No AI tools were utilized for language polishing, translation, data analysis or any form of writing assistance during the manuscript preparation. AI tools did not participate in the design of the study or the interpretation of the research results in any way. All images included in the manuscript are original and were not generated by any AI tools.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Zhebei Mingzhou Hospital, Huzhou, approval No. 2025050.
Informed consent statement: All study participants and their legal guardians provided written informed consent before recruitment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Corresponding author: Li-Dan Chen, Research Fellow, Department of Emergency, Xuchang Central Hospital, No. 30 Huatuo Road, Weidu District, Xuchang 461000, Henan Province, China. chendanxcszxyy@sina.com
Received: January 27, 2026
Revised: February 10, 2026
Accepted: March 5, 2026
Published online: June 27, 2026
Processing time: 144 Days and 16 Hours
Revised: February 10, 2026
Accepted: March 5, 2026
Published online: June 27, 2026
Processing time: 144 Days and 16 Hours
Core Tip
Core Tip: Diabetes mellitus acted as a significant independent risk factor in postoperative infectious complications reported in patients with gastric or colorectal cancer. Importantly, the patients with a known history of diabetes, characterized by elevated preoperative glycated hemoglobin A1c ≥ 7.0%, and hypoalbuminaemia (albumin < 35 g/L) displayed a higher risk of postoperative infectious complications. Surgical site infection was the most common postoperative infection, followed by pulmonary infection. Early identification, preoperative optimization of blood glucose and nutritional status, and targeted perioperative management might help to reduce the incidence of postoperative infections and improve overall patient outcomes.