Analysis of quality of life and reflux oesophagitis following Billroth II and Roux-en-Y gastrointestinal reconstruction for gastric cancer

Table 1 Comparison of clinical baseline characteristics between groups, n (%)

Items	Research group (n = 50)	Control group (n = 50)	t/χ2	P value
Sex
Male	28 (56.0)	29 (58.0)	0.108	0.084
Female	22 (44.0)	21 (42.0)
Age, year, mean ± SD	51.26 ± 4.57	51.43 ± 4.61	0.229	0.104
BMI, kg/m2, mean ± SD	20.61 ± 1.25	20.78 ± 1.18	0.317	0.091
TNM stage
I	5 (10.0)	7 (14.0)	0.806	0.773
II	35 (70.0)	33 (66.0)
III	10 (20.0)	10 (20.0)
Longest diameter of the tumour, cm, mean ± SD	3.14 ± 0.58	3.11 ± 0.66	0.477	0.116
Tumour location
Gastric antrum/gastric angle	39 (78.0)	40 (80.0)	0.916	0.265
Body of stomach	11 (22.0)	10 (20.0)

BMI: Body mass index.

Table 2 Comparison of postoperative reflux occurrence between groups, mean ± SD

Group	Case	Number of reflux episodes within 24 hours	> 5 minutes reflux frequency	Longest duration of reflux (minutes)
Research group	50	5.14 ± 1.25	1.05 ± 0.58	5.71 ± 1.03
Control group	50	7.02 ± 1.17	2.36 ± 0.41	6.33 ± 1.21
t		7.772	13.041	2.761
P value		0.000	0.000	0.006

Table 3 Comparison of postoperative reflux symptom scores between groups, points, mean ± SD

Group	Case	Heartburn	Acid reflux	Upper abdominal distension	Upper abdominal pain
Research Group	50	1.14 ± 0.25	1.08 ± 0.37	1.22 ± 0.41	1.06 ± 0.26
Control group	50	2.01 ± 0.34	1.95 ± 0.40	2.03 ± 0.37	1.94 ± 0.18
t		14.571	11.290	10.372	19.681
P value		0.000	0.000	0.001	0.000

Table 4 Comparison of postoperative nutritional indicator levels between groups, mean ± SD

Group	Case	Hb (g/L)		ALB (g/L)		PA (mg/L)
		Post-4 weeks	Post-8 weeks	Post-8 weeks	Post-8 weeks	Post-8 weeks	Post-8 weeks
Research group	50	62.18 ± 5.37	81.16 ± 6.14a	37.73 ± 3.11	52.18 ± 4.98a	292.74 ± 11.46	332.47 ± 13.16a
Control group	50	63.07 ± 5.73	80.47 ± 6.23a	37.91 ± 3.18	51.23 ± 4.17a	292.09 ± 11.24	330.87 ± 12.76a
t		0.801	0.561	0.292	1.033	0.289	0.623
P value		0.425	0.578	0.775	0.301	0.771	0.538

^aP < 0.05 vs 4 weeks post-surgery within the group.

ALB: Albumin; PA: Prealbumin; Hb: Haemoglobin.

Table 5 Comparison of postoperative quality of life between groups

Group	Case	Bodily functions		Role function		Cognitive function		Emotional function		Social function
		Post-4 weeks	Post-8 weeks	Post-4 weeks	Post-8 weeks	Post-4 weeks	Post-8 weeks	Post-4 weeks	Post-8 weeks	Post-4 weeks	Post-8 weeks
Research group	50	51.45 ± 3.22	73.42 ± 4.19a	51.84 ± 2.36	73.11 ± 3.48a	50.78 ± 3.86	70.45 ± 3.12a	51.22 ± 2.29	75.74 ± 3.62a	50.19 ± 3.18	71.12 ± 4.29a
Control group	50	51.63 ± 3.14	62.35 ± 4.23a	51.92 ± 2.28	60.71 ± 3.17a	50.86 ± 3.75	60.13 ± 3.24a	51.89 ± 2.31	63.68 ± 3.46a	50.22 ± 3.24	60.63 ± 4.13a
t		0.281	13.152	0.168	18.619	0.112	16.229	1.460	17.032	0.052	12.501
P value		0.780	0.001	0.863	0.001	0.917	0.000	0.148	0.001	9.963	0.000

^aP < 0.05 vs 4 weeks post-surgery within the group.

Table 6 Postoperative incidence of reflux oesophagitis between groups, n (%)

Group	Case	Reflux oesophagitis
Research group	50	2 (4.0)
Control group	50	9 (16.0)
χ2		8.169
P value		0.010