Effect of graded nutritional intervention on elderly colorectal cancer patients’ postop status

Table 1 Comparison of baseline data between the two groups

Group	n	Sex (cases)		Age (years), mean ± SD	Tumor type (cases)		Clinical staging (cases)		Education level (cases)
		Male	Female		Colon cancer	Rectal cancer	Stage I	Stage II	Junior high school or lower	Senior high school	University or higher
Research group	61	35	26	73.66 ± 4.82	31	30	26	35	16	28	17
Control group	65	36	29	73.31 ± 5.76	39	26	32	33	14	30	21
χ2/t	-	0.051		0.369	1.074		0.553		0.497
P value	-	0.822		0.713	0.300		0.457		0.780

Table 2 Clinical indicators of the two groups, mean ± SD

Group	n	Postoperative time to passage of gas by anus (hour)	Fever (cases)	Duration of fever (hour)	Length of hospital stay (day)	Hospitalization costs (ten thousand yuan)
Research group	61	52.63 ± 8.22	6	49.68 ± 6.01	6.51 ± 0.73	4.25 ± 0.66
Control group	65	67.45 ± 7.68	15	64.33 ± 5.37	8.47 ± 0.95	5.33 ± 0.79
χ2/t	-	10.463	3.972	14.447	12.925	6.224
P value	-	< 0.001	0.046	< 0.001	< 0.001	< 0.001

Table 3 Comparison of nutritional status between the two groups, mean ± SD

Group	n	Hb (g/L)		PAB (mg/L)		TRF (g/L)		PG-SGA (points)
		Pre-intervention	Post-intervention	Pre-intervention	Post-intervention	Pre-intervention	Post-intervention	Pre-intervention	Post-intervention
Research group	61	102.33 ± 10.52	121.67 ± 13.13	152.32 ± 18.71	245.54 ± 23.01	1.41 ± 0.15	2.31 ± 0.20	10.29 ± 1.33	4.55 ± 0.48
Control group	65	104.28 ± 9.47	113.46 ± 14.85	151.78 ± 16.52	210.37 ± 22.41	1.42 ± 0.13	1.98 ± 0.12	10.31 ± 1.48	5.81 ± 0.56
t	-	1.095	3.279	0.172	8.690	0.401	11.311	0.080	13.519
P value	-	0.276	0.001	0.864	< 0.001	0.689	< 0.001	0.967	< 0.001

Hb: Hemoglobin; PAB: Prealbumin; TRF: Transferrin; PG-SGA: Patient-Generated Subjective Global Assessment.

Table 4 Comparison of immune response between the two groups, mean ± SD

Group	n	IgG (g/L)		IgA (g/L)		IgM (g/L)
		Pre-intervention	Post-intervention	Pre-intervention	Post-intervention	Pre-intervention	Post-intervention
Research group	61	6.25 ± 0.59	8.40 ± 0.87	1.32 ± 0.15	1.64 ± 0.18	1.23 ± 0.11	1.51 ± 0.19
Control group	65	6.21 ± 0.68	7.31 ± 0.91	1.36 ± 0.13	1.41 ± 0.13	1.20 ± 0.09	1.32 ± 0.15
t	-	0.352	6.864	1.602	8.260	1.680	6.250
P value	-	0.726	< 0.001	0.112	< 0.001	0.096	< 0.001

Ig: Immunoglobulin G.

Table 5 Comparison of inflammatory indicators between the two groups, mean ± SD

Group	n	NF-κB (U/L)		IL-1 (g/L)		IL-8 (μg/L)		TNF-α (μg/L)
		Pre-intervention	Post-intervention	Pre-intervention	Post-intervention	Pre-intervention	Post-intervention	Pre-intervention	Post-intervention
Research group	61	17.55 ± 1.83	13.21 ± 1.02	50.48 ± 5.92	32.18 ± 3.88	29.28 ± 2.50	22.12 ± 2.08	61.35 ± 6.14	48.71 ± 6.94
Control group	65	17.63 ± 1.25	15.08 ± 1.23	51.12 ± 6.48	40.75 ± 4.11	29.85 ± 2.63	25.81 ± 2.16	60.89 ± 5.87	52.64 ± 7.18
t	-	0.288	9.257	0.578	12.018	1.245	9.756	0.430	3.120
P value	-	0.774	< 0.001	0.565	< 0.001	0.215	< 0.001	0.668	< 0.001

NF-κB: Nuclear factor kappa B; IL: Interleukin; TNF-α: Tumor necrosis factor-α.