Diagnostic challenge of gastritis cystica profunda with secondary abscess formation: A case report

Figure 1 Gastroscopy showing a submucosal bulge in the gastric antrum. A: White-light gastroscopy revealed congestion and edema of the gastric antral mucosa, with a 4-cm submucosal bulge on the anterior wall; B: Close-up view of the lesion; C: Optical electronic chromoendoscopy demonstrated the micro-surface and microvascular structures of the lesion; D: Application of pressure with a pair of biopsy forceps confirmed a soft texture.

Figure 2 Contrast-enhanced computed tomography images. A: Plain computed tomography showed significant thickening of the anterior wall of the gastric body and antrum with low-density areas; B: The mucosal line appeared continuous, with the lesion in the submucosa surrounded by patchy edema; C: In the arterial phase, multiple submucosal cystic lesions of varying sizes were visible in the anterior wall of the gastric antrum, with ring-like enhancement of the cyst walls; D: In the venous phase, the cyst walls exhibited persistent enhancement; in contrast, the cyst contents remained non-enhancing.

Figure 3 Routine pathology and immunohistochemistry. A: Hematoxylin and eosin staining, 10 ×. Histology revealed multiple cystic spaces in the submucosa, with cyst walls lined by columnar epithelium, accompanied by neutrophil infiltration and abscess formation; B: Immunostaining, 10 ×. Immunohistochemistry showed a Ki-67 index of approximately 1%.