Cui Q, He K, Chen MS, Huang LD. Diagnostic challenge of gastritis cystica profunda with secondary abscess formation: A case report. World J Gastrointest Surg 2025; 17(11): 110075 [DOI: 10.4240/wjgs.v17.i11.110075]
Corresponding Author of This Article
Li-Dan Huang, MD, Associate Chief Physician, Department of Radiology, Shaoxing Central Hospital, No. 1 Huayu Road, Keqiao District, Shaoxing 312000, Zhejiang Province, China. 13735288701@163.com
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Gastroenterology & Hepatology
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Case Report
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Nov 27, 2025 (publication date) through Nov 25, 2025
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World Journal of Gastrointestinal Surgery
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1948-9366
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Cui Q, He K, Chen MS, Huang LD. Diagnostic challenge of gastritis cystica profunda with secondary abscess formation: A case report. World J Gastrointest Surg 2025; 17(11): 110075 [DOI: 10.4240/wjgs.v17.i11.110075]
World J Gastrointest Surg. Nov 27, 2025; 17(11): 110075 Published online Nov 27, 2025. doi: 10.4240/wjgs.v17.i11.110075
Diagnostic challenge of gastritis cystica profunda with secondary abscess formation: A case report
Qian Cui, Kai He, Min-Shi Chen, Li-Dan Huang
Qian Cui, Kai He, Min-Shi Chen, Li-Dan Huang, Department of Radiology, Shaoxing Central Hospital, Shaoxing 312000, Zhejiang Province, China
Author contributions: Cui Q contributed to clinical information collection and original draft writing; He K and Chen MS analyzed the histopathological and immunohistochemical results; Huang LD revised the manuscript. All authors reviewed and approved the final version of the manuscript.
Informed consent statement: Informed written consent was obtained from the patient for the publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li-Dan Huang, MD, Associate Chief Physician, Department of Radiology, Shaoxing Central Hospital, No. 1 Huayu Road, Keqiao District, Shaoxing 312000, Zhejiang Province, China. 13735288701@163.com
Received: May 29, 2025 Revised: June 18, 2025 Accepted: September 18, 2025 Published online: November 27, 2025 Processing time: 180 Days and 18.3 Hours
Abstract
BACKGROUND
Gastritis cystica profunda (GCP) is a rare submucosal gastric lesion characterized by the extension of cystically dilated gastric mucosal glands into or below the muscularis mucosa, often due to various underlying causes. Typically, asymptomatic or associated with mild symptoms, GCP is most commonly discovered incidentally during surgery or endoscopy. To the best of our knowledge, this is the first documented case of GCP accompanied by acute inflammation and abscess formation.
CASE SUMMARY
A 37-year-old woman presented with upper abdominal pain. Laboratory tests showed elevated inflammatory markers and carbohydrate antigen 19-9 levels. Gastroscopy revealed a submucosal bulge. Based on enhanced computed tomography findings, an ectopic pancreas with cyst was suspected. Clinically, we decided to perform distal gastrectomy. Postoperative pathology confirmed that the patient had GCP complicated by acute inflammation and abscess formation. The patient had an uneventful postoperative recovery.
CONCLUSION
This case provides information on new complications of GCP and emphasizes the diagnostic value of enhanced computed tomography.
Core Tip: Gastritis cystica profunda (GCP) is a rare submucosal lesion of the stomach, and its etiology and pathogenesis remain unclear. It is generally considered benign, and no standardized treatment protocol currently exists. We report a case of GCP complicated by acute inflammation and abscess formation, successfully treated with partial gastrectomy. This case highlights a previously unreported complication of GCP and underscores the diagnostic utility of enhanced computed tomography for GCP.
