Truong A, Hanna MH, Moghadamyeghaneh Z, Stamos MJ. Implications of preoperative hypoalbuminemia in colorectal surgery. World J Gastrointest Surg 2016; 8(5): 353-362 [PMID: 27231513 DOI: 10.4240/wjgs.v8.i5.353]
Corresponding Author of This Article
Michael J Stamos, MD, Division of Colon and Rectal Surgery, Department of Surgery, University of California, Irvine Medical Center, 33 City Blvd West Suite 1600, Orange, CA 92868, United States. mstamos@uci.edu
Research Domain of This Article
Surgery
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. May 27, 2016; 8(5): 353-362 Published online May 27, 2016. doi: 10.4240/wjgs.v8.i5.353
Implications of preoperative hypoalbuminemia in colorectal surgery
Adam Truong, Mark H Hanna, Zhobin Moghadamyeghaneh, Michael J Stamos
Adam Truong, Mark H Hanna, Zhobin Moghadamyeghaneh, Michael J Stamos, Division of Colon and Rectal Surgery, Department of Surgery, University of California, Irvine Medical Center, Orange, CA 92868, United States
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Michael J Stamos, MD, Division of Colon and Rectal Surgery, Department of Surgery, University of California, Irvine Medical Center, 33 City Blvd West Suite 1600, Orange, CA 92868, United States. mstamos@uci.edu
Telephone: +1-714-4566262
Received: October 19, 2015 Peer-review started: October 21, 2015 First decision: December 28, 2015 Revised: January 7, 2016 Accepted: March 7, 2016 Article in press: March 9, 2016 Published online: May 27, 2016 Processing time: 210 Days and 22.5 Hours
Core Tip
Core tip: Although albumin remains a flawed marker of nutrition, it offers clear prognostic value in predicting patient outcomes after colorectal surgery. Hypoalbuminemia significantly influences the length of hospital stay, rates of surgical site infections, enterocutaneous fistula risk, and deep vein thrombosis formation. Despite the fact that hypoalbuminemia is classically defined < 3.0 g/dL, clinical judgment must account for albumin levels ≤ 3.4 g/dL as even modest hypoalbuminemia can affect outcomes. The subjective global assessmen, modified Glasgow Prognostic Score, and Colorectal preoperative Surgical Score scoring systems provide convenient and valuable prognostic information that may help in the counseling and risk adjustment of patients undergoing colorectal surgery.
