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World J Gastrointest Surg. Mar 27, 2026; 18(3): 115191
Published online Mar 27, 2026. doi: 10.4240/wjgs.v18.i3.115191
Risk factors and nomogram prediction of postoperative incisional hernia following liver transplantation: A retrospective cohort study
Si-Yuan Liu, Xin-Yue Xie, Kun-Ning Zhang, Yong-Qiang Ma, Abdisamat Ababakri, Hai-Zhou Hao, Li Zhang, Qing-Jun Guo, Xing-Hui Yu, Yan Xie, Wen-Tao Jiang
Si-Yuan Liu, Nankai University, Tianjin 300192, China
Xin-Yue Xie, Abdisamat Ababakri, Hai-Zhou Hao, Li Zhang, Qing-Jun Guo, Yan Xie, Wen-Tao Jiang, Department of Liver Transplantation, Tianjin First Central Hospital, Tianjin 300192, China
Kun-Ning Zhang, Yong-Qiang Ma, School of Medicine, Nankai University, Tianjin 300192, China
Xing-Hui Yu, Department of Kidney Transplantation, Tianjin First Central Hospital, Tianjin 300192, China
Co-first authors: Si-Yuan Liu and Xin-Yue Xie.
Co-corresponding authors: Yan Xie and Wen-Tao Jiang.
Author contributions: Liu SY and Xie XY contributed equally to this work as co-first authors; Zhang KN and Ma YQ conceived and designed the study; Ababakri A and Hao HZ collected and curated the clinical data; Zhang L performed the statistical analysis and developed the nomogram model; Guo QJ contributed to data interpretation and figure preparation; Yu XH, Xie Y, and Jiang WT critically revised the manuscript for important intellectual content; Xie Y and Jiang WT contributed equally as co-corresponding authors. All authors read and approved the final version of the manuscript.
Supported by Tianjin Bureau Science and Technology Project, No. 23JCZDJC01200; Tianjin Bureau Health Science and Technology Project, No. TJWJ2024MS017; Independent Research Fund of the Institute of Transplant Medicine at Nankai University, No. NKTM2023004; Scientific Research Plan of Tianjin Municipal Education Commission, No. 2024ZX013; General Project of the China Medicine Education Association, No. ZJWYH-2023-YIZHI-028; and Tianjin Key Medical Discipline Construction Project, No. TJYXZDXK-3-006A-1.
Institutional review board statement: This study was approved by the Ethics Committee of Tianjin First Central Hospital, No. YC-BY-LC-2023-038.
Informed consent statement: The requirement for informed consent was waived due to the retrospective design of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: The datasets generated and analyzed during the current study are available from the corresponding author on reasonable request. Individual de-identified participant data and statistical codes used in this study can be provided for academic research purposes upon approval of a formal proposal.
Corresponding author: Wen-Tao Jiang, PhD, Chief Physician, Dean, Full Professor, Department of Liver Transplantation, Tianjin First Central Hospital, No. 2 Baoshan West Road, Xiqing District, Tianjin 300192, China. jiangwentao@nankai.edu.cn
Received: October 14, 2025
Revised: November 13, 2025
Accepted: January 15, 2026
Published online: March 27, 2026
Processing time: 168 Days and 10.1 Hours
Core Tip

Core Tip: This study developed and validated a nomogram that incorporates key factors, including age, hepatitis, ascites, hypoalbuminemia, elevated alanine aminotransferase, and prolonged prothrombin time, to accurately predict the risk of incisional hernia following liver transplantation, facilitating the identification of high-risk patients for targeted preventive management. The nomogram developed in this study provides a valuable tool for individualized postoperative management and preventive strategies.