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World Journal of Gastrointestinal Surgery
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1948-9366
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jan 27, 2026; 18(1): 114059
Published online Jan 27, 2026. doi: 10.4240/wjgs.v18.i1.114059
Interventional management of acute perforated cholecystitis: When is percutaneous transhepatic cholecystostomy a reasonable therapeutic option?
Theodoros Kolokotronis, Dimitrios Pantelis
Theodoros Kolokotronis, Department of Surgery and Centre of Minimal Invasive Surgery, GFO Kliniken Bonn, Bonn 53225, North Rhine-Westphalia, Germany
Dimitrios Pantelis, Department of General and Visceral Surgery, GFO Kliniken Bonn, Bonn 53225, North Rhine-Westphalia, Germany
Author contributions: Kolokotronis T performed the literature review, analyzed the data and wrote the manuscript; Pantelis D critically revised the manuscript. All authors approve the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Theodoros Kolokotronis, MD, PhD, Department of Surgery and Centre of Minimal Invasive Surgery, GFO Kliniken Bonn, Street Josef Hospital Bonn-Beuel, Hermann Street 37, Bonn 53225, North Rhine-Westphalia, Germany. fernado13984@yahoo.gr
Received: September 16, 2025
Revised: October 2, 2025
Accepted: November 3, 2025
Published online: January 27, 2026
Processing time: 133 Days and 2.9 Hours
Core Tip

Core Tip: While early laparoscopic cholecystectomy remains the gold standard, critically ill patients with perforated cholecystitis may benefit from minimally invasive strategies such as percutaneous transhepatic cholecystostomy or endoscopic ultrasound-guided gallbladder drainage, as bridging or definitive therapy. However, more evidence is needed concerning which subgroup of patients benefit from those non-surgical modalities.
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