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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2025; 17(9): 110064
Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.110064
Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.110064
Mesenteric-guided approach to pyloric lymphadenectomy in laparoscopic radical gastrectomy
Guo-Feng Pan, Wei-Hong Zhang, Zhi-Ming Cai, Jian Chen, Ji-Huang Wu, Jian-Bin Weng, Zi-Peng Zhu, Zhi-Xing Guo, Jian-Jin Lin, Zhi-Xiong Li, Yan-Chang Xu, Department of Gastrointestinal Surgery Unit 1, Teaching Hospital of Putian First Hospital of Fujian Medical University, Putian 351100, Fujian Province, China
Guo-Feng Pan, Department of Gastroenterological Surgery Unit 1, Putian First Hospital, The Affiliated Hospital of Putian University, Putian 351100, Fujian Province, China
Guo-Feng Pan, Department of Gastrointestinal Surgery, Institute of Minimally Invasive Surgery of Putian University, Putian 351100, Fujian Province, China
Co-first authors: Guo-Feng Pan and Wei-Hong Zhang.
Author contributions: Pan GF and Zhang WH contributed equally to this article, they are the co-first authors of this manuscript; Pan GF, Zhang WH, and Xu YC designed the research study; Cai ZM, Chen J, Wu JH, Weng JB, Zhu ZP, Guo ZX, and Lin JJ performed the research; Pan GF, Zhang WH, and Li ZX analyzed the data and wrote the manuscript; Xu YC supervised the project; and all authors have read and approved the final manuscript.
Supported by the Natural Science Foundation Program in Fujian Province of China, No. 2023J011726.
Institutional review board statement: This study was approved by the Medical Ethics Committee of First Hospital of Putian Cit, approval No. 2024-180.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at xyc202301@163.com.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan-Chang Xu, Department of Gastrointestinal Surgery Unit 1, Teaching Hospital of Putian First Hospital of Fujian Medical University, No. 449 Nanmen West Road, Chengxiang District, Putian 351100, Fujian Province, China. xyc202301@163.com
Received: May 28, 2025
Revised: June 16, 2025
Accepted: August 1, 2025
Published online: September 27, 2025
Processing time: 119 Days and 0.7 Hours
Revised: June 16, 2025
Accepted: August 1, 2025
Published online: September 27, 2025
Processing time: 119 Days and 0.7 Hours
Core Tip
Core Tip: This study introduces a mesentery-guided approach to pyloric lymphadenectomy in laparoscopic gastrectomy, centered on defining anatomical landmarks within the right gastro-omental mesentery. By integrating complete mesogastric excision into the standard D2 dissection, this technique enhances the retrieval of No. 6 lymph nodes, reduces operative time and blood loss, and significantly lowers postoperative complication rates. The standardized procedure provides both surgical precision and oncologic potential, offering a valuable strategy for improving outcomes in minimally invasive gastric cancer surgery.