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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2025; 17(9): 106913
Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.106913
Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.106913
Effects of stellate ganglion block anesthesia on cognition and biomarkers in patients undergoing gastrointestinal surgery
Ming-Min Yang, Xue Yan, Department of Anesthesiology, The Third Affiliated Hospital of Nanchang University, The First Hospital of Nanchang, Nanchang 330008, Jiangxi Province, China
Wei Tu, Department of General Surgery, The Third Affiliated Hospital of Nanchang University, The First Hospital of Nanchang, Nanchang 330008, Jiangxi Province, China
Author contributions: Yang MM designed the study and was involved in data collection and manuscript preparation; Yang MM, Tu W and Yan X contributed to the review of the manuscript; all authors have read the manuscript and approved to submit the final version.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of The Third Affiliated Hospital of Nanchang University, The First Hospital of Nanchang (No. IIT2025009).
Informed consent statement: All study participants, or their legal guardians, provided written informed consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xue Yan, BA, Research Fellow, Department of Anesthesiology, The Third Affiliated Hospital of Nanchang University, The First Hospital of Nanchang, No. 128 Xiangshan North Road, Donghu District, Nanchang 330008, Jiangxi Province, China.
Received: May 14, 2025
Revised: June 14, 2025
Accepted: July 21, 2025
Published online: September 27, 2025
Processing time: 133 Days and 0.8 Hours
Revised: June 14, 2025
Accepted: July 21, 2025
Published online: September 27, 2025
Processing time: 133 Days and 0.8 Hours
Core Tip
Core Tip: Stellate ganglion block (SGB) anesthesia has remarkable advantages when used in gastrointestinal surgery. In contrast to general anesthesia, SGB effectively stabilizes patient hemodynamics throughout the perioperative phase. Our results showed that using SGB significantly reduced oxidative stress, as evidenced by lower levels of related biomarkers. This not only safeguards cognitive function, but also actively promotes the recovery of gastrointestinal function, presenting a more optimal choice for enhancing patient management and postoperative outcomes.