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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2025; 17(9): 106258
Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.106258
Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.106258
Long-term outcomes after open total pericystectomy for cystic echinococcosis
Tristan Wagner, Sebastian Struck, Thomas Schmidt, Marielle Hummels, Christiane J Bruns, Dirk L Stippel, Michael N Thomas, Department of General, Visceral, Thoracic and Transplantsurgery, University of Cologne, Cologne 50923, North Rhine-Westphalia, Germany
Thorsten Persigehl, Department of Diagnostic and Interventional Radiology, University of Cologne, Cologne 50923, North Rhine-Westphalia, Germany
Thorsten Persigehl, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Cologne 50923, North Rhine-Westphalia, Germany
Dirk Nierhoff, Department of Gastroenterology and Hepatology, University of Cologne, Cologne 50923, North Rhine-Westphalia, Germany
Co-corresponding authors: Tristan Wagner and Michael N Thomas.
Author contributions: Wagner T and Thomas MN designed the study; Struck S, Thomas MN, Schmidt T, Stippel DL were responsible for developing the methodology; Persigehl T, Hummels M, Wagner T, Nierhoff D, Bruns CJ participated in the formal analysis and investigation; Wagner T and Struck S wrote the draft; Wagner T, Schmidt T, Thomas MN, Stippel DL participated in the review and editing.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of the University of Cologne (23-1371-retro).
Informed consent statement: Signed informed consent was obtained from all participants.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tristan Wagner, Department of General, Visceral, Thoracic and Transplantsurgery, University of Cologne, Kerpener Street 62, Cologne 50923, North Rhine-Westphalia, Germany. tristan.wagner@uk-koeln.de
Received: February 24, 2025
Revised: April 13, 2025
Accepted: August 1, 2025
Published online: September 27, 2025
Processing time: 216 Days and 13.6 Hours
Revised: April 13, 2025
Accepted: August 1, 2025
Published online: September 27, 2025
Processing time: 216 Days and 13.6 Hours
Core Tip
Core Tip: This study presents the largest cohort of standardized open total pericystectomies for cystic echinococcosis, demonstrating its effectiveness in achieving complete cyst removal while preserving liver tissue. Total pericystectomy has evolved as a superior surgical approach, showing significantly lower recurrence rates compared to conservative techniques. Despite concerns about bile leakage and cholestasis, our cohort experienced a low incidence of postoperative bile leakage. With a median 8-year follow-up, the recurrence rate was 0%, highlighting the procedure’s efficacy even in multiple cyst cases. These findings support total pericystectomy as a reliable and durable treatment option for hepatic cystic echinococcosis.