Wang FL, Tang XX, Wu R, Gao YJ, Liu YR, Wang L, Zou XP, Zhang B. Quality of life and outcomes in patients undergoing endoscopic papillectomy vs surgical treatment for duodenal papillary adenomas. World J Gastrointest Surg 2025; 17(6): 106637 [DOI: 10.4240/wjgs.v17.i6.106637]
Corresponding Author of This Article
Bin Zhang, PhD, Doctor, Department of Gastroenterology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, No. 321 Zhongshan Road, Nanjing 210008, Jiangsu Province, China. billzhangnju@foxmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Jun 27, 2025; 17(6): 106637 Published online Jun 27, 2025. doi: 10.4240/wjgs.v17.i6.106637
Quality of life and outcomes in patients undergoing endoscopic papillectomy vs surgical treatment for duodenal papillary adenomas
Feng-Lan Wang, Xiao-Xuan Tang, Rui Wu, Yu-Jia Gao, Yi-Ran Liu, Lei Wang, Xiao-Ping Zou, Bin Zhang
Feng-Lan Wang, Xiao-Xuan Tang, Rui Wu, Yu-Jia Gao, Yi-Ran Liu, Lei Wang, Xiao-Ping Zou, Bin Zhang, Department of Gastroenterology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, Jiangsu Province, China
Xiao-Ping Zou, Department of Gastroenterology, Taikang Xianlin Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, Jiangsu Province, China
Co-first authors: Feng-Lan Wang and Xiao-Xuan Tang.
Co-corresponding authors: Xiao-Ping Zou and Bin Zhang.
Author contributions: Zhang B, Zou XP, and Wang L contributed to conceptualization and supervision; Wu R, Gao YJ, and Liu YR contributed to data collection; Wang FL and Tang XX contributed to data analysis; Wang FL, Tang XX, and Zhang B contributed to literature review; Wang FL contributed to manuscript drafting; all authors contributed to manuscript revision and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Nanjing Drum Tower Hospital, the Affiliated Hospital of Medical School, Nanjing University (Approval No. 2024-351-01).
Informed consent statement: Patients were not required to provide informed consent for the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent. Verbal consent was obtained from the patient during a follow-up call.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
Data sharing statement: The dataset generated and analyzed during the current study is not publicly available due to patient privacy restrictions and ongoing data collection for research purposes but is available from the corresponding author (Zhang B, billzhangnju@foxmail.com) upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bin Zhang, PhD, Doctor, Department of Gastroenterology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, No. 321 Zhongshan Road, Nanjing 210008, Jiangsu Province, China. billzhangnju@foxmail.com
Received: March 4, 2025 Revised: April 4, 2025 Accepted: April 27, 2025 Published online: June 27, 2025 Processing time: 88 Days and 6 Hours
Core Tip
Core Tip: The detection of duodenal papillary adenomas has increased due to advancements in endoscopic techniques, although the prevalence of this condition remains low. Traditionally, surgical resection is the primary treatment, but it has significant drawbacks, such as trauma and high complication rates. Endoscopic removal methods have gained popularity because they are less invasive and better preserve postoperative quality of life. Our study uniquely compared postoperative quality of life and long-term outcomes between patients who received endoscopic and surgical treatments, identifying key factors that affect quality of life after treatment. This research supports endoscopic therapy as a patient-centered approach for managing these adenomas, highlighting the balance between curative intent and quality of life preservation.
