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World J Gastrointest Surg. May 27, 2025; 17(5): 105295
Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.105295
Controversies and consensus surrounding laparoscopic pylorus-preserving gastrectomy for early gastric cancer
Ying-Xuan Ye, Chu-Ying Wu, Li-Quan Chen, Si-Jia Wu, Kai Ye
Ying-Xuan Ye, School of Medicine, South China University of Technology, Guangzhou 510000, Guangdong Province, China
Chu-Ying Wu, Li-Quan Chen, Kai Ye, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, Fujian Province, China
Si-Jia Wu, Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, Fujian Province, China
Co-first authors: Ying-Xuan Ye and Chu-Ying Wu.
Author contributions: Ye YX and Wu CY contributed equally to the study, contributed to original draft preparation, writing, and review; Chen LQ contributed to writing, review, and editing; Wu SJ contributed to writing, review; Ye K contributed to conceptualization, supervision, and funding acquisition; all authors have read and agreed to the published version of the manuscript.
Supported by Quanzhou Science and Technology Plan Projects, No. 2024NY033; Fujian Provincial Health and Youth Research Project, No. 2022QH1117; and Key Clinical Specialty Discipline Construction Program of Fujian (Fujian Health Medicine and Politics), No. [2022]884.
Conflict-of-interest statement: All authors report no conflicts of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kai Ye, MD, PhD, Associate Professor, Chief Physician, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Fujian Medical University, No. 950 Donghai Street, Quanzhou 362000, Fujian Province, China. medwcy@163.com
Received: January 18, 2025
Revised: February 28, 2025
Accepted: March 10, 2025
Published online: May 27, 2025
Processing time: 125 Days and 23.4 Hours
Core Tip

Core Tip: Pylorus-preserving gastrectomy (PPG) is indicated for early-stage gastric cancer located in the middle part of the stomach. This article reviewed the definition and indications, safety profile, benefits, technical considerations, methods for digestive tract reconstruction and postoperative complications associated with laparoscopic PPG on the basis of the latest relevant guidelines and research findings.