Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. May 27, 2025; 17(5): 105220
Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.105220
Diagnostic challenges and radiological insights of rare hepatic perivascular epithelioid cell tumor: A case report and review of the literature
Jun-An Zhou, Zheng-Chao Fan, Ru-Jun Zheng, Qin-Xi Guo, Song Su
Jun-An Zhou, Ru-Jun Zheng, Song Su, Department of General Surgery (Hepatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
Zheng-Chao Fan, Department of Ultrasound, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
Qin-Xi Guo, Department of Pathology, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
Co-first authors: Jun-An Zhou and Zheng-Chao Fan.
Author contributions: Zhou JA and Fan ZC contributed equally to this study as co-first authors; Zhou JA and Zheng RJ were responsible for the overall management of the patient and wrote the manuscript; Fan ZC provided interpretations of the imaging findings; Guo QX provided pathological expertise and interpretations; Su S contributed to manuscript revisions; all authors reviewed and approved the final manuscript.
Supported by National Natural Science Foundation of China, No. U22A2039.
Informed consent statement: Written informed consent was obtained from the patient for the publication of this case report, including all relevant medical data and accompanying images. The patient was informed that her personal information would remain confidential and that all efforts would be made to protect her privacy.
Conflict-of-interest statement: The authors declare no conflicts of interest related to the publication of this case report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Song Su, MD, Professor, Department of General Surgery (Hepatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, No. 25 Taiping Street, Luzhou 646000, Sichuan Province, China. 13882778554@163.com
Received: January 15, 2025
Revised: February 27, 2025
Accepted: March 21, 2025
Published online: May 27, 2025
Processing time: 128 Days and 15.4 Hours
Core Tip

Core Tip: Hepatic perivascular epithelioid cell tumor is a rare liver tumor with nonspecific clinical and imaging features, often leading to misdiagnosis. This case highlights the importance of combining radiological and immunohistochemical evaluations for accurate diagnosis. The significant growth of the lesion observed in this patient emphasizes the need for timely surgical intervention. Long-term follow-up is essential to monitor for recurrence or metastasis.