Letter to the Editor
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Apr 27, 2025; 17(4): 102144
Published online Apr 27, 2025. doi: 10.4240/wjgs.v17.i4.102144
Important issues on the prevention of surgical site infections and the management of prophylactic antibiotics
Xue-Lu Yu, Jian-Hui Peng, Qing Chang, Jing-Wen Chen, Ji-Shun Yang, Ming-Ke Wang
Xue-Lu Yu, Jing-Wen Chen, Ji-Shun Yang, Ming-Ke Wang, Naval Medical Center of People’s Liberation Army, Naval Medical University, Shanghai 200052, China
Jian-Hui Peng, Department of Quality Management, Guangdong Second Provincial General Hospital, Guangzhou 510317, Guangdong Province, China
Qing Chang, The Third Department of Convalescence, Beidaihe Rehabilitation and Convalescence Center of People’s Liberation Army, Qinhuangdao 066000, Hebei Province, China
Jing-Wen Chen, School of Pharmacy, Bengbu Medical University, Bengbu 233000, Anhui Province, China
Co-first authors: Xue-Lu Yu and Jian-Hui Peng.
Co-corresponding authors: Ji-Shun Yang and Ming-Ke Wang.
Author contributions: Wang MK and Yang JS conceptualized, designed, and revised the manuscript; Yu XL and Peng JH drafted the manuscript; Chang Q and Chen JW collected and summarized the literature. All authors have read and approved the final manuscript. Yu XL and Peng JH wrote the draft and contributed equally to this work as co-first authors. Both Wang MK and Yang JS conceptualized, proposed, and supervised the entire process of preparing this manuscript, and played important and indispensable roles in the manuscript preparation and revision as the co-corresponding authors. Wang MK applied for and obtained the funds for this research project. Wang MK conceptualized, designed, and supervised the entire process of the project. He searched the literature, and revised and submitted the early drafts of the manuscript. Yang JS was instrumental and responsible for the comprehensive literature search, preparation, and submission of the current version of the manuscript. This collaboration between Wang MK and Yang JS is crucial for the publication of this manuscript and other manuscripts under preparation.
Supported by Scientific Research Foundation of Shanghai Municipal Health Commission of Changning District, No. 20234Y038; and Medical Science and Technology Research Foundation of Guangdong Province, China, No. C2022023.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ming-Ke Wang, MD, PhD, Associate Chief Physician, Naval Medical Center of People’s Liberation Army, Naval Medical University, No. 338 Huaihai West Road, Changning District, Shanghai 200052, China. wmke021@163.com
Received: October 9, 2024
Revised: January 6, 2025
Accepted: February 8, 2025
Published online: April 27, 2025
Processing time: 170 Days and 16.1 Hours
Core Tip

Core Tip: The occurrence of surgical site infections is associated with patient’s characteristics and surgical factors. Preventive strategies such as risk assessment, disinfection, and enhanced nutrition are essential to reducing the incidence of surgical site infections and healthcare expenditures and improving patient’s clinical outcome. In addition, the use of prophylactic antibiotics should be individualized and precise.