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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Dec 27, 2025; 17(12): 112887
Published online Dec 27, 2025. doi: 10.4240/wjgs.v17.i12.112887
Published online Dec 27, 2025. doi: 10.4240/wjgs.v17.i12.112887
Intraductal papillary neoplasm of the biliary tract with typical clinicopathological, endoscopic features: A case report
Tian-Yuan Gu, Si-Qi Zhao, Min-Jie Chen, Xiao-Ping Li, Zheng-Wei Song, Fei Chen, Department of Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing 314000, Zhejiang Province, China
Su-Hang Wang, Department of Pathology, The Second Affiliated Hospital of Jiaxing University, Jiaxing 314000, Zhejiang Province, China
Shu-Ying Yang, Xiao-Xia Gu, Department of Intensive Medicine, The Second Affiliated Hospital of Jiaxing University, Jiaxing 314000, Zhejiang Province, China
Co-first authors: Tian-Yuan Gu and Su-Hang Wang.
Co-corresponding authors: Xiao-Xia Gu and Fei Chen.
Author contributions: Gu TY, Wang SH, Yang SY, Song ZW, Gu XX and Chen F designed the report; Gu TY, Yang SY and Zhao SQ were attending doctors for the patient; Song ZW performed the surgery; Wang SH performed the pathological examination; Chen MJ and Li XP performed the literature review; Gu TY and Wang SH wrote the draft; Gu XX, Song ZW and Chen F revised the manuscript for important intellectual content; all authors read and approved the final manuscript; Gu TY and Wang SH contributed equally and shared co-first authorship; Gu XX and Chen F contributed equally and shared the corresponding author.
Supported by Medical Health Science and Technology Project of Zhejiang Provincial Health Commission, No. 2022KY1246; and Science and Technology Bureau of Jiaxing City, No. 2023AZ31002.
Informed consent statement: Written informed consent was obtained from the individual for the publication of this case report and any potentially identifiable images. The patient agreed to participate in this study and to publish this report.
Conflict-of-interest statement: The authors report no conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fei Chen, PhD, Department of Surgery, The Second Affiliated Hospital of Jiaxing University, No. 1518 Huancheng North Road, Jiaxing 314000, Zhejiang Province, China. tangchouer@zjxu.edu.cn
Received: August 8, 2025
Revised: October 2, 2025
Accepted: October 29, 2025
Published online: December 27, 2025
Processing time: 139 Days and 8.4 Hours
Revised: October 2, 2025
Accepted: October 29, 2025
Published online: December 27, 2025
Processing time: 139 Days and 8.4 Hours
Core Tip
Core Tip: Owing to the absence of specific clinical and imaging manifestations, intraductal papillary mucinous neoplasm of the biliary tract (IPMN-B) is frequently missed or misdiagnosed when incidentally discovered. Here, we present a case of IPMN-B that exhibited characteristic clinical, imaging, endoscopic, and pathological features and progressed to malignancy. This case illustrates the 4-year latent progression of IPMN-B from an initially 'benign' cystic lesion to a malignant neoplasm, emphasizing the importance of continuous monitoring for nonspecific imaging findings.