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World J Gastrointest Surg. Dec 27, 2025; 17(12): 111262
Published online Dec 27, 2025. doi: 10.4240/wjgs.v17.i12.111262
Intraoperative endoscopy: A controversial tool or a necessity in modern esophagogastric surgery?
Emmanuel Pikoulis, Constantinos Nastos, Panagis M Lykoudis, Nikolaos Pararas, Despoina Myoteri, Anastasia Pikouli, Zoi Gkiafi, Charalampos M Charalampous, Ioannis Margaris, Dionysios Dellaportas
Dionysios Dellaportas, Anastasia Pikouli, Nikolaos Pararas, Constantinos Nastos, Emmanuel Pikoulis, 3rd Department of Surgery, University Hospital “Attikon”, School of Medicine, National and Kapodistrian University of Athens, Athens 12462, Attikí, Greece
Ioannis Margaris, Charalampos M Charalampous, Zoi Gkiafi, Panagis M Lykoudis, 4th Department of Surgery, University Hospital “Attikon”, School of Medicine, National and Kapodistrian University of Athens, Athens 12462, Attikí, Greece
Despoina Myoteri, Department of Pathology, Aretaieion University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens 11528, Attikí, Greece
Panagis M Lykoudis, Division of Surgery and Interventional Science, University College London, London WC1E 6BT, United Kingdom
Author contributions: Dellaportas D, Pikouli A, Myoteri D, Pararas N, Lykoudis PM, Nastos C and Pikoulis E made critical revisions related to important intellectual content of the manuscript; Dellaportas D, Lykoudis PM, and Pikoulis E conceptualized and designed the study; Margaris I, Charalampous CM and Gkiafi Z conducted the literature review, acquired the data and drafted the article; Pikouli A and Myoteri D did the interpretation of data; Pararas N and Nastos C did the analysis of data. All authors have read and approved the final manuscript for publication.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Panagis M Lykoudis, MD, PhD, 4th Department of Surgery, University Hospital “Attikon”, School of Medicine, National and Kapodistrian University of Athens, 1 Rimini Street, Athens 12462, Attikí, Greece. p.lykoudis@ucl.ac.uk
Received: June 26, 2025
Revised: July 22, 2025
Accepted: October 11, 2025
Published online: December 27, 2025
Processing time: 181 Days and 17.1 Hours
Core Tip

Core Tip: Endoscopy is indispensable for the evaluation of foregut conditions, supporting the formulation of a tailored plan for each surgical candidate. It provides live detailed visualization of tumor margins while it also enhances staging accuracy and risk stratification. Moreover, its utility in the management of postoperative complications in the hands of the operating surgeon is of paramount importance. Fellowships in upper gastrointestinal surgery underline the role of intraoperative endoscopy and scientific surgical societies are in alignment with the above views.