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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Oct 27, 2025; 17(10): 111558
Published online Oct 27, 2025. doi: 10.4240/wjgs.v17.i10.111558
Published online Oct 27, 2025. doi: 10.4240/wjgs.v17.i10.111558
Advancements in endoscopic resection of gastrointestinal stromal tumors: Techniques, outcomes, and perspectives
Jie Wu, Department of Respiratory and Oncology, The 72nd Group Army Hospital of PLA, Huzhou 313000, Zhejiang Province, China
Zhen-Dong Jin, Department of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai 200433, China
Author contributions: Jie W and Jin ZD contributed equally to the conception and design of the manuscript; Jie W conducted the literature review and drafted the initial version of the manuscript; Jin ZD critically revised the manuscript for important intellectual content and supervised the entire project. Both authors approved the final version of the manuscript for submission.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhen-Dong Jin, Department of Gastroenterology, Changhai Hospital, Naval Medical University, No. 168 Changhai Road, Yangpu District, Shanghai 200433, China.
Received: July 3, 2025
Revised: July 15, 2025
Accepted: August 26, 2025
Published online: October 27, 2025
Processing time: 113 Days and 17.6 Hours
Revised: July 15, 2025
Accepted: August 26, 2025
Published online: October 27, 2025
Processing time: 113 Days and 17.6 Hours
Core Tip
Core Tip: Endoscopic resection has emerged as a promising, minimally invasive treatment for gastrointestinal stromal tumors (GISTs). Techniques like endoscopic submucosal dissection, submucosal tunneling endoscopic resection, and endoscopic full-thickness resection have shown favorable outcomes, including high rates of complete tumor removal, reduced recovery times, and preservation of gastric function. This review explores the advancements in these techniques, highlighting their safety, efficacy, and the growing role of endoscopy in GIST management. Key factors for selecting the appropriate resection method depend on tumor size, location, and patient-specific factors.