BPG is committed to discovery and dissemination of knowledge
Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Oct 27, 2025; 17(10): 107760
Published online Oct 27, 2025. doi: 10.4240/wjgs.v17.i10.107760
Effect of totally thoracoscopic esophagectomy on postoperative complications and serum inflammatory factors in patients with early esophageal cancer
Heng-Chi Zhao, Shuang Zhang, Lin Zhou, Xiao-Long Lou, Dong Chen, Cheng-Wei Shi, Zhe Ren
Heng-Chi Zhao, Xiao-Long Lou, Dong Chen, Cheng-Wei Shi, Zhe Ren, Department of Cardiothoracic Surgery, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310000, Zhejiang Province, China
Shuang Zhang, Lin Zhou, Department of Second Surgery, Shengzhou Hospital of Traditional Chinese Medicine, Shaoxing 312400, Zhejiang Province, China
Co-first authors: Heng-Chi Zhao and Shuang Zhang.
Author contributions: Zhao HC wrote the manuscript and reviewed the manuscript; Zhao HC Zhang S contributed equally to this article, they are the co-first authors of this manuscript; Zhao HC, Zhang S, Zhou L, Lou XL, Chen D, Shi CW, and Ren Z collected the data; and all authors annotated the manuscript.
Supported by Zhejiang Provincial Traditional Chinese Medicine Science and Technology Plan Project, No. 2023ZL424.
Institutional review board statement: This study was approved by the Medical Ethics Committee of The First Affiliated Hospital of Zhejiang Chinese Medical University.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhe Ren, Associate Professor, Department of Cardiothoracic Surgery, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), No. 54 Youdian Road, Hangzhou 310000, Zhejiang Province, China. rzhe2046@sina.com
Received: May 20, 2025
Revised: June 22, 2025
Accepted: August 6, 2025
Published online: October 27, 2025
Processing time: 156 Days and 22.8 Hours
Core Tip

Core Tip: Currently, evidence on totally thoracoscopic esophagectomy for early esophageal cancer is limited. This study confirms that compared to conventional surgery, this approach minimizes incision size, decreases hospitalization, reduces complications, lessens pain on postoperative day 3, and attenuates inflammatory stress. The finding supports its role as a clinically superior approach and a valuable reference for optimizing treatment strategies while furnishing practitioners with clinically relevant reference data.