Case Control Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2023; 15(8): 1615-1628
Published online Aug 27, 2023. doi: 10.4240/wjgs.v15.i8.1615
Post-transplant biliary complications using liver grafts from deceased donors older than 70 years: Retrospective case-control study
Carlos Jimenez-Romero, Iago Justo-Alonso, Pilar del Pozo-Elso, Alberto Marcacuzco-Quinto, Cristina Martín-Arriscado-Arroba, Alejandro Manrique-Municio, Jorge Calvo-Pulido, Alvaro García-Sesma, Ricardo San Román, Oscar Caso-Maestro
Carlos Jimenez-Romero, Iago Justo-Alonso, Pilar del Pozo-Elso, Alberto Marcacuzco-Quinto, Alejandro Manrique-Municio, Jorge Calvo-Pulido, Alvaro García-Sesma, Oscar Caso-Maestro, Unit of HPB Surgery and Abdominal Organs Transplantation, `12 de Octubre´ University Hospital, Madrid 28041, Spain
Cristina Martín-Arriscado-Arroba, Clinical Research Unit (I+12), `12 de Octubre´ University Hospital, Madrid 28041, Spain
Ricardo San Román, Department of Radiology, `12 de Octubre´ University Hospital, Madrid 28041, Spain
Author contributions: Jimenez-Romero C and Caso-Maestro O designed the research and wrote the paper; Jimenez-Romero C, Justo-Alonso I, san Román R and Caso-Maestro O analyzed data; Justo-Alonso I, del Pozo-Elso P, Marcacuzco-Quinto A, Manrique-Municio A, Calvo-Pulido J and García-Sesma A collected data; Martín-Arriscado-Arroba C peformed the statistical analysis.
Institutional review board statement: The study was reviewed and approved by the `12 de Octubre´ University Hospital Institution Review Board.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous data that were collected after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Technical appendix, statistical code, and dataset is available from the corresponding author if required.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Oscar Caso-Maestro, MD, PhD, Associate Professor, Surgeon, Unit of HBP Surgery and Abdominal Organs Transplantation, ‘12 de Octubre’ University Hospital, Av. Córdoba s/n, Madrid 28041, Spain. oscarcasomaestro@hotmail.com
Received: January 19, 2023
Peer-review started: January 19, 2023
First decision: March 14, 2023
Revised: March 27, 2023
Accepted: June 25, 2023
Article in press: June 25, 2023
Published online: August 27, 2023
Processing time: 217 Days and 16.6 Hours
Core Tip

Core Tip: The shortage of liver grafts and subsequent waitlist mortality led us to expand the donor pool using liver grafts from older donors. Some authors have proposed a higher incidence of biliary complications (BC) using advanced age donors. In our experience, the incidence of BC was low on using liver grafts > 70 year (8.4%). Patient and graft survival were similar to patients without biliary complications and most of them could be managed by percutaneous dilation or Roux-en-Y hepaticojejunostomy.