Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Dec 27, 2020; 12(12): 549-554
Published online Dec 27, 2020. doi: 10.4240/wjgs.v12.i12.549
Giant simple hepatic cyst with multiple elevated serum tumor markers: A case report
Jia-Wei Zhang, Cheng Peng, Yan-Shuo Ye, Wei Li
Jia-Wei Zhang, Cheng Peng, Yan-Shuo Ye, Wei Li, Department of Hepatobiliary-Pancreatic Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China
Jia-Wei Zhang, Department of Vascular Surgery, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Cheng Peng, Department of Hepatobiliary-Pancreatic Surgery, The Third Xiangya Hospital of Central South University, Changsha 410013, Hunan Province, China
Author contributions: Zhang JW initially identified the case, collected and organized the medical records, and performed an intensive revision of the manuscript; Peng C primarily drafted the article, accomplished the actual writing, selected the references, and drafted the discussion; Ye YS also performed the revision of the manuscript; Li W contributed to the conceptual design, and carried out critical revision and finalization of the manuscript.
Supported by Nature Science Foundation of The Science and Technology Bureau of Jilin Province, No. Li 20190201227JC; and The Innovation Capacity Building Fund of The Development and Reform Commission of Jilin Province, No. Li 2019C015.
Informed consent statement: The patient provided informed written consent for the publication of this case report.
Conflict-of-interest statement: None.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei Li, MD, PhD, Professor, Surgeon, Department of Hepatobiliary-Pancreatic Surgery, China-Japan Union Hospital of Jilin University, No. 126 Xiantai Street, Changchun 130033, Jilin Province, China. weili888@jlu.edu.cn
Received: July 23, 2020
Peer-review started: July 23, 2020
First decision: October 6, 2020
Revised: October 16, 2020
Accepted: November 12, 2020
Article in press: November 12, 2020
Published online: December 27, 2020
Processing time: 151 Days and 11.5 Hours
Core Tip

Core Tip: Simple hepatic cysts typically appear as asymptomatic benign tumors of the liver without elevation of any diagnostic serum biomarkers. However, over the years, a few cases of simple hepatic cysts with elevated tumor markers have been reported in the world. Here, we report a case of giant simple hepatic cyst with elevation of multiple serum cancer biomarkers, including protein induced by vitamin K absence-II, cancer antigen (CA) 12-5, and CA19-9.