Published online Jul 27, 2022. doi: 10.4240/wjgs.v14.i7.696
Peer-review started: April 15, 2022
First decision: May 12, 2022
Revised: May 26, 2022
Accepted: June 22, 2022
Article in press: June 22, 2022
Published online: July 27, 2022
Processing time: 102 Days and 14.9 Hours
Skeletal muscle metastasis (SMM) is a rare complication of colorectal adenocarcinomas. The study was conducted to explore, in more detail, the present literature of this unusual finding.
The study encompassed a thorough review of the present literature on SMM due to colorectal adenocarcinoma. Our goal was to highlight the significance of this type of metastasis and increase awareness for early diagnosis and detection.
The aim of this study was to review the literature for cases of SMM from colorectal adenocarcinoma.
A systematic literature search was carried out in December 2021. The search strategy was standardized using the PRISMA guidelines.
SMM were most commonly detected in the thigh muscles. Most of the tumours originated from the rectum or the right colon. The mean time interval between the primary lesion and onset of SMM was 22 mo.
Our review showed that SMM from colorectal adenocarcinomas is a rare complication. However, it is possible that the low incidence could be due to under-reporting. Early use of advanced imaging techniques, like fluorodeoxyglucose-positron emission tomography, and a high index of clinical suspicion might increase the reporting of SMM from colorectal adenocarcinoma.
This study again highlights that there is a paucity of literature on SMM after colorectal adenocarcinoma. This is certainly a field that needs more research in the future.