Huang YH, Ma L, Cao B, Zhang YJ, Gao Q, Zhu ZM, Qiao XL, Wang L, He BG. Endoscopic and laparoscopic treatment of ileocecal laterally spreading tumor with concomitant appendiceal adenoma: A case report and review of literature. World J Gastrointest Surg 2025; 17(9): 109952 [DOI: 10.4240/wjgs.v17.i9.109952]
Corresponding Author of This Article
Bao-Guo He, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, No. 1677 Wutaishan Road, Qingdao 266000, Shandong Province, China. hebaoguo@qduhospital.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Sep 27, 2025; 17(9): 109952 Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.109952
Endoscopic and laparoscopic treatment of ileocecal laterally spreading tumor with concomitant appendiceal adenoma: A case report and review of literature
Ying-Hui Huang, Li Ma, Bin Cao, Yue-Juan Zhang, Qun Gao, Zhen-Ming Zhu, Xiao-Lu Qiao, Lei Wang, Bao-Guo He
Ying-Hui Huang, Bin Cao, Qun Gao, Zhen-Ming Zhu, Xiao-Lu Qiao, Lei Wang, Bao-Guo He, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Li Ma, Department of Clinical Nutrition, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Yue-Juan Zhang, Department of Pathology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Author contributions: Huang YH wrote the manuscript; He BG performed the surgery; Ma L reviewed and edited the manuscript; Cao B done the supervision; Zhang YJ finished the pathology diagnose section; Gao Q, Zhu ZM, Qiao XL, and Wang L helped in data collection. All authors approved the final version.
Informed consent statement: All the operations involved in this article have obtained the informed consent of the patients.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bao-Guo He, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, No. 1677 Wutaishan Road, Qingdao 266000, Shandong Province, China. hebaoguo@qduhospital.cn
Received: June 4, 2025 Revised: June 24, 2025 Accepted: July 31, 2025 Published online: September 27, 2025 Processing time: 113 Days and 1.1 Hours
Abstract
BACKGROUND
Ileocecal laterally spreading tumors (LSTs) complicated by appendiceal tubular adenoma are rare and challenging to diagnose because of the absence of typical symptoms and specific diagnostic signs. Traditionally, the primary treatment has been laparoscopic appendectomy (LA).
CASE SUMMARY
A 63-year-old female presented with changes in bowel habits. Colonoscopy revealed an ileocecal LST. The patient underwent endoscopic submucosal dissection. Postoperative follow-up colonoscopy revealed mucosal elevation at the appendiceal orifice, with pathology confirming tubular adenoma. Abdominal computed tomography indicated a suspicious appendiceal tumor, leading to LA with partial cecectomy. The postoperative recovery was uneventful. At the 1-year follow-up, colonoscopy revealed no evidence of tumor recurrence.
CONCLUSION
Ileocecal LSTs with appendiceal tubular adenomas are traditionally treated with LA. endoscopic submucosal dissection can also yield favorable outcomes.
Core Tip: Ileocecal laterally spreading tumors with appendiceal tubular adenoma are rare and hard to diagnose due to nonspecific symptoms. Traditionally treated by laparoscopic appendectomy, new research shows endoscopic submucosal dissection can be effective. This case innovatively applied sequential endoscopic submucosal dissection for high-grade dysplastic lesions at the appendiceal orifice, followed by appendectomy preserving the ileocecal valve. This approach improved postoperative quality of life and presents a novel strategy for deep-seated appendiceal lesions, addressing visualization challenges in deep lumen extension.
