Published online Feb 27, 2025. doi: 10.4240/wjgs.v17.i2.99581
Revised: December 11, 2024
Accepted: December 25, 2024
Published online: February 27, 2025
Processing time: 76 Days and 2.4 Hours
The development of hepatocellular carcinoma (HCC) is influenced by multiple factors. Interventional therapy offers an effective treatment option for patients with unresectable intermediate-to-advanced HCC. Interventional therapy can induce electrocardiographic (ECG) abnormalities that may be associated with liver dysfunction, electrolyte disorders, and cardiac injury.
To explore the ECG alterations and determinants following interventional therapy in patients with HCC.
Sixty patients undergoing interventional treatment for liver cancer were selected as study participants. According to the results of the dynamic ECG examination 1 day after surgery, the patients were divided into an abnormal group (n = 21) and a nonabnormal group (n = 39). With the help of dynamic ECG examination, the ECG parameters were compared and the baseline data of patients was recorded in the two groups.
The 24 hours QT interval variability, 24 hours normal atrial polarization to ventricular polarization (R-R) interval (standard deviation), 24 hours consecutive 5 minutes normal R-R interval, and 24 hours continuous 5 minutes normal R-R interval (standard deviation mean) were lower than patients in the nonabnormal group (P < 0.05). The logistic analysis showed that age > 60 years, liver function grade B, and postoperative body temperature 38 °C were risk factors for abnormal dynamic electrocardiogram in patients with liver cancer intervention (P < 0.05).
Interventional therapy for HCC can lead to ECG abnormalities, underscoring the clinical need for enhanced cardiac monitoring to mitigate myocardial complications.
Core Tip: The Electrocardiographic abnormalities of liver cancer patients should be clarified as soon as possible, and targeted intervention measures are needed for the risk factors affecting their electrocardiographic abnormalities, especially for those undergoing interventional therapy.