Lv LL, Ying XX, Wu HM, Shi XY, Zhang QQ, Zhao H. Postoperative recovery and bleeding risk after endoscopic snare cold resection in patients with 5-15 mm colorectal polyps. World J Gastrointest Surg 2025; 17(10): 108664 [DOI: 10.4240/wjgs.v17.i10.108664]
Corresponding Author of This Article
Hong Zhao, PhD, Department of Gastroenterology, Dongyang People’s Hospital, East 6 Ward, No. 60 Wuning West Road, Dongyang 322100, Zhejiang Province, China. zhaoh199010@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Oct 27, 2025 (publication date) through Oct 24, 2025
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Journal Information of This Article
Publication Name
World Journal of Gastrointestinal Surgery
ISSN
1948-9366
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Lv LL, Ying XX, Wu HM, Shi XY, Zhang QQ, Zhao H. Postoperative recovery and bleeding risk after endoscopic snare cold resection in patients with 5-15 mm colorectal polyps. World J Gastrointest Surg 2025; 17(10): 108664 [DOI: 10.4240/wjgs.v17.i10.108664]
Li-Li Lv, Xiao-Xuan Ying, Huang-Min Wu, Hong Zhao, Department of Gastroenterology, Dongyang People’s Hospital, Dongyang 322100, Zhejiang Province, China
Xiang-Yu Shi, Qing-Qing Zhang, Department of Gastroenterology, Yiwu Tianxiang Medical East Hospital, Yiwu 322100, Zhejiang Province, China
Author contributions: Lv LL designed the research study; Lv LL, Ying XX, Wu HM, Shi XY, Zhang QQ, and Zhao H performed the primary literature review and data extraction; Lv LL, Ying XX, Wu HM, Shi XY, Zhang QQ, and Zhao H analyzed the data and wrote the manuscript; Lv LL revised the manuscript for important intellectual content. All authors have read and approved the final version.
Institutional review board statement: This study was reviewed and approved by the Science and Research Office of Dongyang People’s Hospital, No. 2025-YX-070.
Informed consent statement: All study participants or their legal guardians provided written informed consent for personal and medical data collection before enrollment.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong Zhao, PhD, Department of Gastroenterology, Dongyang People’s Hospital, East 6 Ward, No. 60 Wuning West Road, Dongyang 322100, Zhejiang Province, China. zhaoh199010@163.com
Received: June 13, 2025 Revised: July 20, 2025 Accepted: August 25, 2025 Published online: October 27, 2025 Processing time: 132 Days and 17.5 Hours
Abstract
BACKGROUND
Endoscopic cold snare resection (CSP) can enhance postoperative recovery and minimize bleeding risk in patients with 5-15 mm colorectal polyps. However, more detailed evaluations are required to assess their advantages over conventional methods.
AIM
To evaluate the effects of endoscopic CSP on postoperative recovery and bleeding risk in patients with 5-15 mm colorectal polyps.
METHODS
This randomized controlled study included 193 patients (mean age: 57.91 ± 5.41 years; 97 men and 96 women) with 5-15 mm colorectal polyps treated at Dongyang People's Hospital between March and June 2023. The patients were randomly assigned to the experimental group (n = 100), who underwent CSP, and the control group (n = 93), who underwent conventional endoscopic mucosal resection (EMR). Operation time, hospital stay, dietary status, and bleeding rate within 3 days were compared.
RESULTS
The CSP group had significantly shorter operation times (15.02 ± 2.44 minutes vs 18.78 ± 5.48 minutes, P < 0.001) and hospital stays (3.11 ± 1.08 days vs 4.89 ± 1.35 days, P < 0.001) than the EMR group. The fasting rate on the day of surgery was also lower in the CSP group (P < 0.05). The complete resection rates were similar between groups (98.00% vs 94.62%, P = 0.210), and no perforations occurred in either group. The 3-day postoperative bleeding rate was slightly lower in the CSP group (2.00%) than in the EMR group (6.45%), although this difference was not statistically significant (P = 0.234), indicating limited clinical relevance.
CONCLUSION
CSP was safe and efficient for removing 5-15 mm colorectal polyps, offering faster recovery and comparable safety to EMR. The procedural efficiency of CSP supports its broad clinical application.
Core Tip: We compared endoscopic cold snare polypectomy (CSP) with conventional endoscopic mucosal resection in 193 patients with 5-15 mm colorectal polyps. CSP demonstrated advantages in postoperative recovery, including shorter operative time, reduced hospitalization, and lower fasting rates on the day of surgery. Despite similar complete resection rates and no perforation in both groups, CSP showed a marginally lower but statistically comparable bleeding risk within 3 postoperative days postoperatively. With comparable safety profiles and superior recovery outcomes, CSP has emerged as a practical option for small-to-medium-sized colorectal polyps aligned with fast-track surgical goals.
