Ma LL, Li WN, Lei X, Lin XD, Wu ZW, Xu B, Huang GX. Experience in enteral and parenteral nutrition schemes for familial congenital short bowel syndrome: Two case reports. World J Gastrointest Surg 2025; 17(10): 106689 [DOI: 10.4240/wjgs.v17.i10.106689]
Corresponding Author of This Article
Guo-Xian Huang, Department of Pediatric Surgery, Women and Children’s Hospital, School of Medicine, Xiamen University, No. 10 Zhenhai Road, Xiamen 361003, Fujian Province, China. lazybell@126.com
Research Domain of This Article
Pediatrics
Article-Type of This Article
Case Report
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Oct 27, 2025 (publication date) through Oct 24, 2025
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Journal Information of This Article
Publication Name
World Journal of Gastrointestinal Surgery
ISSN
1948-9366
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Ma LL, Li WN, Lei X, Lin XD, Wu ZW, Xu B, Huang GX. Experience in enteral and parenteral nutrition schemes for familial congenital short bowel syndrome: Two case reports. World J Gastrointest Surg 2025; 17(10): 106689 [DOI: 10.4240/wjgs.v17.i10.106689]
Li-Li Ma, Wen-Ni Li, Xin Lei, Xiang-De Lin, Zhi-Wei Wu, Bo Xu, Guo-Xian Huang, Department of Pediatric Surgery, Women and Children’s Hospital, School of Medicine, Xiamen University, Xiamen 361003, Fujian Province, China
Author contributions: Ma LL contributed significantly to the conception and preparation of this manuscript; Li WN contributed review and editing of this manuscript; Lei X and Lin XD helped the presentation and visualization of the data; Wu ZW helped perform the data curation; Xu B contributed to the management and coordination responsibility for this research; Huang GX helped perform the data curation and visualization.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guo-Xian Huang, Department of Pediatric Surgery, Women and Children’s Hospital, School of Medicine, Xiamen University, No. 10 Zhenhai Road, Xiamen 361003, Fujian Province, China. lazybell@126.com
Received: June 5, 2025 Revised: July 21, 2025 Accepted: September 8, 2025 Published online: October 27, 2025 Processing time: 140 Days and 17.9 Hours
Abstract
BACKGROUND
Congenital short bowel syndrome (CSBS) is a rare disorder characterized by a congenital shortage in the length of the small intestines, resulting in compromised intestinal functionality, frequently accompanied by congenital intestinal malrotation. This study summarizes the experience of enteral and parenteral nutrition (PN) schemes for two cases of CSBS accompanied by intestinal malrotation to provide a reference for this condition.
CASE SUMMARY
Case 1 underwent surgical intervention 23 days after birth, but experienced postoperative intolerance to oral feeding. Consequently, the patient was transitioned to nasal feeding for 6 months while concurrently receiving round-the-clock PN. Despite ongoing adjustments to the caloric intake of enteral and PN throughout the treatment, cholestatic liver injury persisted. Furthermore, this child developed malnutrition by the age of 1 year. Case 2 received surgical intervention on 2 days after birth, demonstrating favorable tolerance for enteral feeding and intermittent PN. The child exhibited satisfactory growth and development without any associated complications.
CONCLUSION
CSBS is rarely encountered in clinical practice and is often accompanied by congenital intestinal malrotation. It can be improved with early diagnosis and active surgical intervention. Thus, we recommend early initiation of total PN, which is a highly effective measure in promoting early growth and development.
Core Tip: Congenital short bowel syndrome (CSBS) is a rare disorder distinguished by the congenital shortage in the length of the small intestines, resulting in compromised intestinal functionality, frequently accompanied by congenital intestinal malrotation. Prompt identification and surgical management of CSBS are crucial in enhancing the overall prognosis of patients affected by this condition. What is new: This paper summarizes the experience of enteral and parenteral nutrition schemes for two cases of CSBS accompanied by intestinal malrotation to provide a reference for this condition.
