Ciriano Hernández P, Martínez Pinedo C, Calcerrada Alises E, García Santos E, Sánchez García S, Picón Rodríguez R, Jiménez Higuera E, Sánchez Peláez D, Herrera Montoro V, Martín Fernández J. Colorectal cancer metastases to the thyroid gland: A case report. World J Gastrointest Surg 2020; 12(3): 116-122 [PMID: 32218894 DOI: 10.4240/wjgs.v12.i3.116]
Corresponding Author of This Article
Patricia Ciriano Hernández, PhD, Surgeon, Department of Surgery, Hospital General Universitario de Ciudad Real, Calle Obispo Rafael Torija, Ciudad Real 13005, Spain. patricia.ciriano.hernandez@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Mar 27, 2020; 12(3): 116-122 Published online Mar 27, 2020. doi: 10.4240/wjgs.v12.i3.116
Colorectal cancer metastases to the thyroid gland: A case report
Patricia Ciriano Hernández, Carlos Martínez Pinedo, Enrique Calcerrada Alises, Esther García Santos, Susana Sánchez García, Rafael Picón Rodríguez, Elisa Jiménez Higuera, Daniel Sánchez Peláez, Violeta Herrera Montoro, Jesús Martín Fernández
Patricia Ciriano Hernández, Carlos Martínez Pinedo, Enrique Calcerrada Alises, Esther García Santos, Susana Sánchez García, Rafael Picón Rodríguez, Elisa Jiménez Higuera, Daniel Sánchez Peláez, Jesús Martín Fernández, Department of Surgery, Hospital General Universitario de Ciudad Real, Ciudad Real 13005, Spain
Violeta Herrera Montoro, Department of Pathology, Hospital General Universitario de Ciudad Real, Ciudad Real 13005, Castilla La Mancha, Spain
Author contributions: Martínez Pinedo C designed the research; Calcerrada Alises E, García Santos E, Sánchez García S, Picón Rodríguez R, Jiménez Higuera E, and Sánchez Peláez D performed the research; Ciriano Hernández P wrote the manuscript; Herrera Montoro V provided the histopathological images; Martín Fernández J supervised the project.
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest statement: No conflicts of interest exist.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Patricia Ciriano Hernández, PhD, Surgeon, Department of Surgery, Hospital General Universitario de Ciudad Real, Calle Obispo Rafael Torija, Ciudad Real 13005, Spain. patricia.ciriano.hernandez@gmail.com
Received: June 29, 2019 Peer-review started: July 1, 2019 First decision: September 10, 2019 Revised: October 1, 2019 Accepted: November 20, 2019 Article in press: November 21, 2019 Published online: March 27, 2020 Processing time: 244 Days and 18.6 Hours
Abstract
BACKGROUND
Secondary malignancies of the thyroid gland are a rare finding in clinical practice. In addition, colorectal metastasis to the thyroid (CMT) is even more infrequently diagnosed. The source of the primary tumor follows demographic and ethnic patterns, which reflects the most prevalent malignancies in the different populations. Colorectal cancer is one of the most common types of cancer worldwide; nevertheless, CMT is infrequently diagnosed. Most of them are identified during the follow-up of gastrointestinal primary malignancies. Due to the improvement of image techniques, oncological treatment, and follow-up, survival and consequent diagnosis of metastatic disease are more frequent. Those facts make this entity a diagnostic and therapeutic challenge, due to the lack of information and the difficulties performing clinical trials and research.
CASE SUMMARY
Here, we present a case report of a patient diagnosed with CMT of adenocarcinoma of the rectum evidenced during follow-up, 4 years after neoadjuvant chemoradiotherapy, who had subsequent curative surgical treatment of the primary tumor and inter-current lung bilateral metastases.
CONCLUSION
Thyroid metastases of extra-thyroid origin are an uncommon finding, even rarer in cases of CMT. The diagnostic process, as well as survival of oncologic patients is improving, and consequently the number of metastases to the thyroid gland is increasing.
Core tip: Thyroid metastases of extra-thyroid origin are an uncommon finding, particularly in cases of gastrointestinal, colon, and rectum malignancies. The diagnostic process, as well as survival of oncological patients is improving. Consequently the number of diagnosed metastases to the thyroid gland is increasing. However, the management and outcome of these patients remain unclear, making it necessary to conduct more clinical research to define diagnostic and therapeutic protocols to provide a suitable treatment and a positive impact on outcome. Our objective was to review the current literature in the context of a recently diagnosed case in our hospital.
