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©The Author(s) 2023.
World J Diabetes. Jun 15, 2023; 14(6): 883-891
Published online Jun 15, 2023. doi: 10.4239/wjd.v14.i6.883
Published online Jun 15, 2023. doi: 10.4239/wjd.v14.i6.883
Indicators | Group A (n = 50) | Group B (n = 50) | Statistical value | P value |
Gender, n (%) | χ2 = 0.164 | 0.685 | ||
Male | 30 (60.00) | 28 (56.00) | ||
Female | 20 (40.00) | 22 (44.00) | ||
Age (mean ± SD, yr) | 43.12 ± 5.02 | 43.25 ± 5.12 | t = 0.128 | 0.898 |
Duration of diabetes (mean ± SD, yr) | 2.1 5 ± 0.52 | 2.23 ± 0.55 | t = 0.747 | 0.457 |
Combined hyperlipidemia, n (%) | χ2 = 0.164 | 0.685 | ||
Yes | 20 (40.00) | 22 (44.00) | ||
No | 30 (60.00) | 28 (56.00) | ||
Combined hypertension, n (%) | χ2 = 0.170 | 0.680 | ||
Yes | 18 (36.00) | 20 (40.00) | ||
No | 32 (64.00) | 30 (60.00) | ||
Urine NAG (mean ± SD, U/L) | 14.05 ± 2.20 | 19.45 ± 3.68 | t = 8.906 | < 0.001 |
Serum RBP (mean ± SD, mg/L) | 43.56 ± 5.50 | 84.98 ± 15.70 | t = 17.606 | < 0.001 |
Variable | B | SE | Wals | P value | OR | 95%CI | |
Upper limit | Lower limit | ||||||
Constant | -9.366 | 1.808 | 26.839 | 0.000 | 0.000 | - | - |
Urine NAG (U/L) | 0.568 | 0.111 | 26.338 | 0.000 | 1.765 | 1.421 | 2.192 |
Serum RBP (mg/L) | 0.346 | 0.109 | 9.996 | 0.002 | 1.413 | 1.141 | 1.751 |
Indicators | AUC | 95%CI of AUC | SE | P value | Cut-off value | Specificity | Sensitivity | Youden index |
Urine NAG | 0.867 | 0.796-0.939 | 0.036 | 0.000 | 11.855 (U/L) | 0.980 | 0.860 | 0.840 |
Serum RBP | 0.951 | 0.902-1.000 | 0.025 | 0.000 | 39.620 (mg/L) | 0.980 | 0.780 | 0.640 |
Combined diagnosis | 0.974 | 0.936-1.000 | 0.020 | 0.000 | - | 0.980 | 0.940 |
- Citation: Lin ZH, Dai SF, Zhao JN, Jiang Y. Application of urinary N-acetyl-β-D-glucosaminidase combined with serum retinol-binding protein in early detection of diabetic nephropathy. World J Diabetes 2023; 14(6): 883-891
- URL: https://www.wjgnet.com/1948-9358/full/v14/i6/883.htm
- DOI: https://dx.doi.org/10.4239/wjd.v14.i6.883