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Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jan 15, 2026; 17(1): 111847
Published online Jan 15, 2026. doi: 10.4239/wjd.v17.i1.111847
Transverse tibial bone transport promotes distraction osteogenesis and improves blood flow in the management of diabetic foot
Mei-Mei Liao, Fan Zhang, Yi-Kai Wang, Meng-Wei Wang, Jia-Rui Cao, Zhi-Hui Jin, Yi-Jun Ren, Sen Chen
Mei-Mei Liao, Department of Ultrasound Imaging, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China
Fan Zhang, Yi-Kai Wang, Meng-Wei Wang, Jia-Rui Cao, Zhi-Hui Jin, Yi-Jun Ren, Sen Chen, Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China
Author contributions: Liao MM and Chen S contributed to the conception, design, data analysis, and manuscript drafting and editing; Liao MM, Zhang F, Wang YK, Wang MW, Cao JR, Jin ZH, Ren YJ, and Chen S contributed to the data collection and assembly and revised the manuscript; Liao MM and Chen S contributed to the conception, resources, and manuscript review and editing; All authors have read and approved the final manuscript.
Supported by General Project of Hubei Provincial Department of Health, No. WJ2021M139.
Institutional review board statement: This study was approved by the Ethics Committee of Renmin Hospital of Wuhan University (Approval No. WDRY2022-K200).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sen Chen, MD, Department of Orthopedics, Renmin Hospital of Wuhan University, No. 238 Jiefang Road, No. 99 Zhangzhidong Road, Wuchang District, Wuhan 430060, Hubei Province, China. chensen1502@outlook.com
Received: August 6, 2025
Revised: September 30, 2025
Accepted: November 19, 2025
Published online: January 15, 2026
Processing time: 160 Days and 19.4 Hours
Core Tip

Core Tip: Current treatment options for diabetic foot (DF) primarily involve glycemic control and surgical intervention; however, these approaches do not address the underlying pathological state of ischemia and hypoxia. Consequently, many patients with refractory DF ultimately require amputation. Transverse tibial bone transport (TTT), initially developed to correct limb deformities, has shown favorable outcomes in research studies. This technique has also been widely applied in managing chronic osteomyelitis due to its advantages, including minimal invasiveness, enhancement of microcirculation, and reconstruction of both osseous and soft tissue defects. This study explored the effects of TTT on treatment outcomes in patients with DF ulcers.